Researcher:
Uçar, Ege Anıl

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Undergraduate Student

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Ege Anıl

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Uçar

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Uçar, Ege Anıl

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20222

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    Antibacdus-pan: antibacterial utilization among adult patients at Koc University Hospital before and during COVID-19 pandemic within 12-months period: a hospital pharmacoepidemiology study
    (Wiley, 2022) Gülmez, Sinem Ezgi; Güldan, Mustafa; Uçar, Ege Anıl; Karakuş, Mehmet Batuhan; Şahin, Selin Merve; Şişman, Uluman; Baygül, Arzu Eden; Faculty Member; Undergraduate Student; Undergraduate Student; Undergraduate Student; Undergraduate Student; Undergraduate Student; Undergraduate Student; Faculty Member; Koç University Research Center for Translational Medicine (KUTTAM) / Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi (KUTTAM); School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; School of Medicine; 281312; N/A; N/A; N/A; N/A; N/A; 272290
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    PublicationOpen Access
    Antipacdus-pan: antibacterial utilization among adult patients before and during COVID-19 Pandemic within 12-months period: a tertiary hospital pharmacoepidemiology study
    (Design Oriented Community (DOC), 2022) Uçar, Ege Anıl; Karakuş, Mehmet Batuhan; Güldan, Mustafa; Şahin, Selin Merve; Şişman, Uluman; Baygül, Arzu Eden; Gülmez, Sinem Ezgi; Undergraduate Student; Undergraduate Student; Undergraduate Student; Faculty Member; Koç University Research Center for Translational Medicine (KUTTAM) / Koç Üniversitesi Translasyonel Tıp Araştırma Merkezi (KUTTAM); School of Medicine; N/A; N/A; N/A; N/A; N/A; 272290; 281312
    Objective: irrational use of antibacterials is a concern during the COVID-19 pandemic. Hospital pharmacoepidemiology studies are important for evaluating the rational use of medicines, especially antibacterials, during pandemics. Defined daily doses (DDD) and drug utilization 90% (DU90%) are established methods for the evaluation of drug utilization. We aimed to evaluate antibacterial utilization in a tertiary hospital setting at Koç University Hospital (KUH). Materials and methods: this cross-sectional, descriptive study was retrospectively conducted with data extracted from KUH Inpatient Electronic Order System (CP) and was carried out for a period of one year. Antibacterial utilization of adult (aged ? 18 years) inpatients, who were prescribed at least one type of systemic antibacterial (ATC code J01), was evaluated using the recommended parameter DDD/100 admission and compared between 6 months before COVID-19 and during COVID-19 periods. March 11, 2020, the very first COVID-19 diagnosed case in Turkey, was set as the cutoff date of the 6-month period for the selection of the compared antibacterials using the DU90% method. Results: finally, 3280 of 5942 and 2605 of 4942 prescriptions for pre-COVID-19 and COVID-19 periods were included, respectively. Antibacterial utilization according to DDD/100 admissions increased from 193.96 to 201.26 DDD/100 admissions after the initiation of COVID-19 pandemic. The most utilized antibacterials were piperacillin and enzyme inhibitors in pre-COVID-19 period, whereas meropenem was utilized the most during COVID-19 period. Azithromycin utilization increased by 656.24%, whereas clarithromycin utilization decreased by 52.12%. Antibacterials were utilized most in general surgery department, with an increase of 17.57%. Conclusion: there is an increase in antibacterial utilization in KUH during COVID-19 pandemic, especially reserved antibacterials, which is a concern for antibacterial resistance.