Researcher:
Imam, Ashraf

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Doctor

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Ashraf

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Imam

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Imam, Ashraf

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2020 - 20213

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Researcher Of Publications: search.filters.isAuthorOfPublication.fabb9c42-d7b4-4edb-b148-f4043f3a57a1

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Now showing 1 - 3 of 3
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    Cardiac intervention before liver transplantation
    (Elsevier Science Inc, 2021) N/A; N/A; Imam, Ashraf; Karataş, Cihan; Mecit, Nesimi; Kalayoğlu, Münci; Kanmaz, Turan; Doctor; Doctor; Doctor; Doctor; Faculty Member; N/A; N/A; N/A; N/A; School of Medicine; Koç University Hospital; Koç University Hospital; Koç University Hospital; Koç University Hospital; N/A; N/A; N/A; N/A; N/A; 275799
    Background. Cardiovascular complication is one of the leading causes of mortality after liver transplantation (LT). Thus, a thorough cardiac evaluation is a must before proceeding to a liver transplant surgery. Percutaneous coronary intervention (PCI) with stent and to a lesser extent coronary artery bypass grafting (CABG) are both valuable treatment options for patients with coronary artery disease. Methods. A retrospective, single-center study that included patients who underwent cardiac intervention and subsequent LT for end-stage liver disease. All patients who had PCI or CABG were included in the study. Results. Twenty-nine adult patients out of 51 had a cardiac intervention before liver transplantation. Twenty-four patients had a diagnostic PCI, 3 patients had therapeutic PCI with stent, and 2 had failed PCI and proceeded to CABG before liver transplant. The mean age of the patients was 60.5 years. There were 24 men. All patients had cirrhosis. The 2 CABG cases were done during the same admission with a 13- and 18-day interval between the CABG and the transplantation. Both cases were live-related liver transplantation. No mortality was reported. Conclusion. In case of PCI failure, CABG may be a valuable and safe treatment option for cirrhotic patients as a preparation for liver transplantation. Live donor liver transplantation may be a good back-up for those patients in case they develop hepatic decompensation.
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    Three consequent pediatric liver transplant deaths in the COVID-19 era
    (Avicenna Organ Transplant Center, 2020) N/A; N/A; Imam, Ashraf; Karataş, Cihan; Imam, Riham; Armutlu, Ayşe; Mecit, Nesimi; Karakaya, Afak Durur; Kalayoğlu, Münci; Kanmaz, Turan; Doctor; Doctor; Other; Teaching Faculty; Doctor; Faculty Member; Doctor; Faculty Member; N/A; N/A; N/A; School of Medicine; N/A; School of Medicine; N/A; School of Medicine; Koç University Hospital; Koç University Hospital; N/A; N/A; Koç University Hospital; N/A; Koç University Hospital; N/A; N/A; N/A; N/A; 133567; N/A; 269567; N/A; 275799
    The effect of COVID-19 on the transplant recipients is not well-established. Many reports underestimate the effect of COVID-19 on the immunosuppressed population. Herein, we report on 3 pediatric liver transplant recipients who were transplanted at our center between February 11 and March 10, 2020-during the COVID-19 pandemic era. The 3 patients aged between 5 and 10 months, had a rapid and aggressive respiratory deterioration that necessitated mechanical ventilation and extracorporeal life support; and eventually died. The clinical and pathological pictures likely represent COVID-19 pneumonia. Chest x-rays showed progressive infiltrates. Lung autopsies showed diffuse alveolar damage in two cases. We concluded that COVID-19 is very likely to have catastrophic effects on transplant recipients.
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    PublicationOpen Access
    Three consequent pediatric liver transplant deaths in the COVID-19 era
    (Avicenna Organ Transplant Institute, 2020) Imam, Ashraf; Karataş, Cihan; Armutlu, Ayşe; Karakaya, Afak Durur; Kalayoğlu, Münci; Kanmaz, Turan; Teaching Faculty; Faculty Member; Faculty Member; Koç University Hospital
    The effect of COVID-19 on the transplant recipients is not well-established. Many reports underestimate the effect of COVID-19 on the immunosuppressed population. Herein, we report on 3 pediatric liver transplant recipients who were transplanted at our center between February 11 and March 10, 2020-during the COVID-19 pandemic era. The 3 patients aged between 5 and 10 months, had a rapid and aggressive respiratory deterioration that necessitated mechanical ventilation and extracorporeal life support; and eventually died. The clinical and pathological pictures likely represent COVID-19 pneumonia. Chest x-rays showed progressive infiltrates. Lung autopsies showed diffuse alveolar damage in two cases. We concluded that COVID-19 is very likely to have catastrophic effects on transplant recipients.