Publication:
Association of borderline intellectual functioning and adverse childhood experience with adult psychiatric morbidity. findings from a British birth cohort

dc.contributor.coauthorHassiotis, Angela
dc.contributor.coauthorBrown, Emma
dc.contributor.coauthorHarris, James
dc.contributor.coauthorHelm, David
dc.contributor.coauthorMünir, Kerim
dc.contributor.coauthorSalvador-Carulla, Luis
dc.contributor.coauthorBertelli, Marco
dc.contributor.coauthorBaghdadli, Amaria
dc.contributor.coauthorWieland, Jannelien
dc.contributor.coauthorNovell-Alsina, Ramon
dc.contributor.coauthorCid, Jordi
dc.contributor.coauthorVerges, Laura
dc.contributor.coauthorMartinez-Leal, Rafael
dc.contributor.coauthorİsmayilov, Fuad
dc.contributor.coauthorEmerson, Eric
dc.contributor.kuauthorMutluer, Tuba
dc.contributor.kuprofileFaculty Member
dc.contributor.unitKoç University Hospital
dc.contributor.yokid305311
dc.date.accessioned2024-11-09T12:42:16Z
dc.date.issued2019
dc.description.abstractBackground: to examine whether Borderline Intellectual Functioning (BIF) and Adverse Childhood Experiences independently predict adult psychiatric morbidity. Methods: we performed a secondary analysis of longitudinal data derived from the 1970 British Birth Cohort Study to examine whether BIF and Adverse Childhood Experiences independently predict adult mental distress as measured by the Malaise Inventory. Factor analysis was used to derive a proxy measure of IQ from cognitive testing at age 10 or 5. Variables that could be indicators of exposure to Adverse Childhood Experiences were identified and grouped into health related and socio-economic related adversity. Results: children with BIF were significantly more likely than their peers to have been exposed to Adverse Childhood Experiences (BIF mean 5.90, non-BIF mean 3.19; Mann-Whitney z = 31.74, p < 0.001). As adults, participants with BIF were significantly more likely to score above the cut-off on the Malaise Inventory. We found statistically significant relationships between the number of socio-economic Adverse Childhood Experiences and poorer adult psychiatric morbidity (r range 0.104-0.141, all p < 001). At all ages the indirect mediating effects of Adverse Childhood Experiences were significantly related to adult psychiatric morbidity. Conclusions: the relationship between BIF and adult psychiatric morbidity appears to be partially mediated by exposure to Adverse Childhood Experiences. Where possible, targeting Adverse Childhood Experiences through early detection, prevention and interventions may improve psychiatric morbidity in this population group.
dc.description.fulltextYES
dc.description.indexedbyWoS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.issue1
dc.description.openaccessYES
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuN/A
dc.description.sponsorshipNCD-Lifespan, Fogarty/NIMH grant at the Boston Children's Hospital, Harvard Medical School
dc.description.sponsorshipGlobal RD0C, Fogarty/NIMH grant at the Boston Children's Hospital, Harvard Medical School
dc.description.sponsorshipInstitut d’Assistència Sanitària, the Government of Catalunya
dc.description.sponsorshipMental Health Policy Unit, the Centre for Disability Research and Policy Faculty of Health Sciences, University of Sydney
dc.description.versionPublisher version
dc.description.volume19
dc.formatpdf
dc.identifier.doi10.1186/s12888-019-2376-0
dc.identifier.embargoNO
dc.identifier.filenameinventorynoIR01991
dc.identifier.issn1471-244X
dc.identifier.linkhttps://doi.org/10.1186/s12888-019-2376-0
dc.identifier.quartileQ2
dc.identifier.scopus2-s2.0-85076166075
dc.identifier.urihttps://hdl.handle.net/20.500.14288/2299
dc.identifier.wos511942900002
dc.keywordsAdversity
dc.keywordsBorderline
dc.keywordsChildhood
dc.keywordsIntellectual
dc.keywordsMental wellbeing
dc.languageEnglish
dc.publisherBioMed Central
dc.relation.grantnoTW98045
dc.relation.grantnoTW009680
dc.relation.urihttp://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/8639
dc.sourceBMC Psychiatry
dc.subjectPsychiatry
dc.titleAssociation of borderline intellectual functioning and adverse childhood experience with adult psychiatric morbidity. findings from a British birth cohort
dc.typeJournal Article
dspace.entity.typePublication
local.contributor.authorid0000-0002-6873-8234
local.contributor.kuauthorMutluer, Tuba

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