Publication:
Dietary protein and muscle wasting in chronic kidney disease: new insights

dc.contributor.coauthorGüngör, Özkan
dc.contributor.coauthorKara, Ali Veysel
dc.contributor.coauthorKalantar Zadeh, Kamyar
dc.contributor.departmentKUH (Koç University Hospital)
dc.contributor.departmentSchool of Medicine
dc.contributor.kuauthorHasbal, Nuri Barış
dc.contributor.schoolcollegeinstituteKUH (KOÇ UNIVERSITY HOSPITAL)
dc.contributor.schoolcollegeinstituteSCHOOL OF MEDICINE
dc.date.accessioned2024-11-09T23:01:37Z
dc.date.issued2023
dc.description.abstractPurpose of review: muscle wasting is an important health problem in chronic kidney disease (CKD) patients. Protein restriction in the diet can be one of the main causes of muscle wasting in this population. In this review, we aimed to investigate the relationship between dietary protein intake and muscle wasting in CKD patients according to recent literature. Recent findings: The one of the main mechanisms responsible for the muscle wasting is the disturbances in skeletal muscle protein turnover. Muscle wasting primarily occurs when the rates of muscle protein breakdown exceed the muscle protein synthesis. Dietary protein intake represents an important role by causing a potent anabolic stimulus resulting a positive muscle protein balance. Compared to studies made in healthy populations, there are very limited studies in the literature about the relationship between dietary protein intake and muscle wasting in the CKD population. Majority of the studies showed that a more liberal protein intake is beneficial for muscle wasting in especially advanced CKD and hemodialysis population. Summary : Although evaluating muscle wasting in CKD patients, the amount of protein in the diet of patients should also be reviewed. Although excessive protein intake has some negative consequences on this patient group, a more liberated dietary protein intake should be taken into account in this patient group with muscle wasting and especially in dialysis patients.
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.issue3
dc.description.openaccessNO
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuN/A
dc.description.volume26
dc.identifier.doi10.1097/MCO.0000000000000903
dc.identifier.eissn1473-6519
dc.identifier.issn1363-1950
dc.identifier.quartileQ3
dc.identifier.scopus2-s2.0-85152174737
dc.identifier.urihttps://doi.org/10.1097/MCO.0000000000000903
dc.identifier.urihttps://hdl.handle.net/20.500.14288/8267
dc.identifier.wos964476100004
dc.keywordsChronic kidney disease
dc.keywordsDietary protein intake
dc.keywordsMuscle wasting
dc.keywordsCatabolic rate
dc.keywordsHemodialysis
dc.keywordsAssociation
dc.keywordsSupplementation
dc.keywordsMortality
dc.keywordsRisk
dc.keywordsMass
dc.language.isoeng
dc.publisherLippincott Williams and Wilkins (LWW)
dc.relation.ispartofCurrent Opinion in Clinical Nutrition and Metabolic Care
dc.subjectMetabolism
dc.subjectNutritional sciences
dc.titleDietary protein and muscle wasting in chronic kidney disease: new insights
dc.typeReview
dspace.entity.typePublication
local.contributor.kuauthorHasbal, Nuri Barış
local.publication.orgunit1SCHOOL OF MEDICINE
local.publication.orgunit1KUH (KOÇ UNIVERSITY HOSPITAL)
local.publication.orgunit2KUH (Koç University Hospital)
local.publication.orgunit2School of Medicine
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