Publication: The role of sodium intake in nephrolithiasis: epidemiology, pathogenesis, and future directions
Program
KU Authors
Co-Authors
Afsar, Baris
Solak, Yalçın
Covic, Adrian
Advisor
Publication Date
Language
English
Type
Journal Title
Journal ISSN
Volume Title
Abstract
The prevalence of nephrolithiasis has doubled over the last decade and the incidence in females nowapproaches that of males. Since dietary salt is lithogenic, a purported mechanism common to both genders is excess dietary sodium intake vis-a-vis processed and fast foods. Nephrolithiasis has far-reaching societal implications such as impact on gross domestic product due to days lost from work (stone disease commonly affects working adults), population-wide carcinogenic diagnostic and interventional radiation exposure (kidney stone disease is typically imaged with computed tomographic imaging and treated under imaging guidance and follow-up), and rising healthcare costs (surgical treatmentwill be indicated for a number of these patients). Therefore, primary prevention of kidney stone disease via dietary intervention is a low-cost public health initiative with massive societal implications. This primer aims to establish baseline epidemiologic and pathophysiologic principles to guide clinicians in sodium-directed primary prevention of kidney stone disease.
Description
Source:
European Journal of Internal Medicine
Publisher:
Elsevier
Keywords:
Subject
Medicine, General and internal medicine