Publication:
Dynamic vs. rigid: transforming the treatment landscape for multisegmental lumbar degeneration

dc.contributor.coauthorAkgul, Turgut
dc.contributor.departmentKUH (Koç University Hospital)
dc.contributor.departmentSchool of Medicine
dc.contributor.departmentKUTTAM (Koç University Research Center for Translational Medicine)
dc.contributor.kuauthorGünerbüyük, Caner
dc.contributor.kuauthorAkgün, Mehmet Yiğit
dc.contributor.kuauthorDurmuş, Nazenin
dc.contributor.kuauthorUçar, Ege Anıl
dc.contributor.kuauthorOrak, Helin İlkay
dc.contributor.kuauthorÖktenoğlu, Bekir Tunç
dc.contributor.kuauthorAteş, Özkan
dc.contributor.kuauthorÖzer, Ali Fahir
dc.contributor.schoolcollegeinstituteKUH (KOÇ UNIVERSITY HOSPITAL)
dc.contributor.schoolcollegeinstituteSCHOOL OF MEDICINE
dc.contributor.schoolcollegeinstituteResearch Center
dc.date.accessioned2025-09-10T04:56:51Z
dc.date.available2025-09-09
dc.date.issued2025
dc.description.abstractBackground: Multisegmental lumbar degenerative disease (ms-LDD) is a common condition in older adults, often requiring surgical intervention. While rigid stabilization remains the gold standard, it is associated with complications such as adjacent segment disease (ASD), higher blood loss, and longer recovery times. The Dynesys dynamic stabilization system offers an alternative by preserving motion while stabilizing the spine. However, data comparing Dynesys with fusion in multisegmental cases are limited. Objective: This study evaluates the clinical and radiographic outcomes of Dynesys dynamic stabilization versus rigid stabilization in the treatment of ms-LDD. Methods: A retrospective analysis was conducted on 53 patients (mean age: 62.25 +/- 15.37 years) who underwent either Dynesys dynamic stabilization (n = 27) or PLIF (n = 26) for ms-LDD involving at least seven motion segments. Clinical outcomes were assessed using the Visual Analog Scale (VAS) and Oswestry Disability Index (ODI), while radiological parameters such as lumbar lordosis (LL), sagittal vertical axis (SVA), and spinopelvic parameters (pelvic incidence, pelvic tilt and, sacral slope) were analyzed. A two-stage surgical approach was employed in the Dynesys group to enhance osseointegration, particularly in elderly osteoporotic patients. Results: Both groups showed significant improvements in VAS and ODI scores postoperatively (p < 0.001), with no significant differences between them. However, the Dynesys group demonstrated superior sagittal alignment correction, with a significant increase in LL (p < 0.002) and a significant decrease in SVA (p < 0.0015), whereas changes in the rigid stabilization group were not statistically significant. Additionally, the Dynesys group had fewer complications, including a lower incidence of ASD (0 vs. 6 cases). The two-stage technique facilitated improved screw osseointegration and reduced surgical risks in osteoporotic patients. Conclusions: Dynesys dynamic stabilization is an effective alternative to rigid stabilization in ms-LDD, offering comparable pain relief and functional improvement while preserving motion and reducing ASD risk. The two-stage approach enhances long-term stability, making it particularly suitable for elderly or osteoporotic patients. Further long-term studies are needed to confirm these findings.
dc.description.fulltextYes
dc.description.harvestedfromManual
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.openaccessGold OA
dc.description.publisherscopeInternational
dc.description.readpublishN/A
dc.description.sponsoredbyTubitakEuN/A
dc.description.versionPublished Version
dc.description.volume14
dc.identifier.doi10.3390/jcm14155472
dc.identifier.eissn2077-0383
dc.identifier.embargoNo
dc.identifier.filenameinventorynoIR06405
dc.identifier.issue15
dc.identifier.quartileQ1
dc.identifier.scopus2-s2.0-105013349489
dc.identifier.urihttps://doi.org/10.3390/jcm14155472
dc.identifier.urihttps://hdl.handle.net/20.500.14288/30200
dc.identifier.wos001552768700001
dc.keywordsMultisegment
dc.keywordsDegenerative disc disease
dc.keywordsDynamic
dc.keywordsStabilization
dc.language.isoeng
dc.publisherMDPI
dc.relation.affiliationKoç University
dc.relation.collectionKoç University Institutional Repository
dc.relation.ispartofJournal of clinical medicine
dc.relation.openaccessYes
dc.rightsCC BY (Attribution)
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectMedicine
dc.titleDynamic vs. rigid: transforming the treatment landscape for multisegmental lumbar degeneration
dc.typeJournal Article
dspace.entity.typePublication
person.familyNameGünerbüyük
person.familyNameAkgün
person.familyNameDurmuş
person.familyNameUçar
person.familyNameOrak
person.familyNameÖktenoğlu
person.familyNameAteş
person.familyNameÖzer
person.givenNameCaner
person.givenNameMehmet Yiğit
person.givenNameNazenin
person.givenNameEge Anıl
person.givenNameHelin İlkay
person.givenNameBekir Tunç
person.givenNameÖzkan
person.givenNameAli Fahir
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