Publication: Gender issues of antibody-mediated diseases in neurology: (NMOSD/autoimmune encephalitis/MG)
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Dargvainiene, Justina
Schneider-Gold, Christiane
Asgari, Nasrin
Ayzenberg, Ilya
Ciplea, Andrea I.
Junker, Ralf
Leypoldt, Frank
Wandinger, Klaus-Peter
Hellwig, Kerstin
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Abstract
Neuromyelitis optica spectrum disorder (NMOSD), autoimmune encephalitis (AE), myasthenia gravis (MG) and Lambert-Eaton myasthenic syndrome (LEMS) are antibody-mediated neurological diseases. They have mostly female predominance, affecting many women during childbearing age. Interactions between the underlying disease (or necessary treatment) and pregnancy can occur in every of these illnesses. Herein, we present the characteristics of NMOSD, AE, MG and LEMS in general, and review published data regarding the influence of the different diseases on fertility, pregnancy, puerperium, treatment strategy during pregnancy and post-partum period, and menopause but also male factors. We summarise key elements that should be borne in mind when confronted with such cases.
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Sage
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Therapeutic Advances in Neurological Disorders
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DOI
10.1177/1756286420949808
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