Publication: Predictors of treatment requirement in HBeAg-negative chronic hepatitis B patients with persistently normal alanine aminotransferase and high serum HBV DNA levels
Program
KU-Authors
KU Authors
Co-Authors
Ormeci, Asli
Aydin, Yucel
Sumnu, Abdullah
Soyer, Ozlem Mutluay
Pinarbasi, Binnur
Gokturk, Suut
Gulluoglu, Mine
Onel, Derya
Badur, Selim
Akyuz, Filiz
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Journal Title
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Alternative Title
Abstract
Objectives: Serum alanine aminotransferase (ALT) is a controversial marker for disease monitoring in hepatitis B e antigen (HBeAg)-negative chronic hepatitis B (CHB) patients. The aim of this study was to determine the fibrosis stage and histological activity index (HAI) in HBeAg-negative CHB patients with persistently normal ALT (PNALT) and high serum HBV DNA (>= 2000 IU/ml) and to investigate clinical risk factors for the requirement of treatment through the examination of liver biopsy specimens.
Source
Publisher
Elsevier Sci Ltd
Subject
Infectious diseases
Citation
Has Part
Source
International Journal of Infectious Diseases
Book Series Title
Edition
DOI
10.1016/j.ijid.2016.09.007
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