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Predictors of treatment requirement in HBeAg-negative chronic hepatitis B patients with persistently normal alanine aminotransferase and high serum HBV DNA levels

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dc.contributor.coauthorOrmeci, Asli
dc.contributor.coauthorAydin, Yucel
dc.contributor.coauthorSumnu, Abdullah
dc.contributor.coauthorSoyer, Ozlem Mutluay
dc.contributor.coauthorPinarbasi, Binnur
dc.contributor.coauthorGokturk, Suut
dc.contributor.coauthorGulluoglu, Mine
dc.contributor.coauthorOnel, Derya
dc.contributor.coauthorBadur, Selim
dc.contributor.coauthorAkyuz, Filiz
dc.contributor.coauthorKaraca, Cetin
dc.contributor.coauthorDemir, Kadir
dc.contributor.coauthorBesisik, Fatih
dc.contributor.coauthorKaymakoglu, Sabahattin
dc.contributor.departmentSchool of Medicine
dc.contributor.kuauthorBaran, Bülent
dc.contributor.schoolcollegeinstituteSCHOOL OF MEDICINE
dc.date.accessioned2024-11-09T22:58:21Z
dc.date.issued2016
dc.description.abstractObjectives: Serum alanine aminotransferase (ALT) is a controversial marker for disease monitoring in hepatitis B e antigen (HBeAg)-negative chronic hepatitis B (CHB) patients. The aim of this study was to determine the fibrosis stage and histological activity index (HAI) in HBeAg-negative CHB patients with persistently normal ALT (PNALT) and high serum HBV DNA (>= 2000 IU/ml) and to investigate clinical risk factors for the requirement of treatment through the examination of liver biopsy specimens.
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.openaccessNO
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuN/A
dc.description.volume52
dc.identifier.doi10.1016/j.ijid.2016.09.007
dc.identifier.eissn1878-3511
dc.identifier.issn1201-9712
dc.identifier.quartileQ1
dc.identifier.scopus2-s2.0-84993978170
dc.identifier.urihttps://doi.org/10.1016/j.ijid.2016.09.007
dc.identifier.urihttps://hdl.handle.net/20.500.14288/7700
dc.identifier.wos389516600014
dc.keywordsChronic hepatitis B
dc.keywordsHBeAg-negative
dc.keywordsPersistently normal ALT
dc.language.isoeng
dc.publisherElsevier Sci Ltd
dc.relation.ispartofInternational Journal of Infectious Diseases
dc.subjectInfectious diseases
dc.titlePredictors of treatment requirement in HBeAg-negative chronic hepatitis B patients with persistently normal alanine aminotransferase and high serum HBV DNA levels
dc.typeJournal Article
dspace.entity.typePublication
local.contributor.kuauthorBaran, Bülent
local.publication.orgunit1SCHOOL OF MEDICINE
local.publication.orgunit2School of Medicine
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relation.isParentOrgUnitOfPublication17f2dc8e-6e54-4fa8-b5e0-d6415123a93e
relation.isParentOrgUnitOfPublication.latestForDiscovery17f2dc8e-6e54-4fa8-b5e0-d6415123a93e

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