Publication:
Effects of integrated inspiratory–expiratory muscle training within hybrid Cardiac rehabilitation following cardiac surgery: a randomized controlled study

dc.contributor.coauthorEksi, B. U.
dc.contributor.coauthorCilbir, C. E.
dc.contributor.coauthorUcgun, H.
dc.contributor.coauthorErtan Harputlu, O.
dc.contributor.coauthorAslan, G. K.
dc.contributor.coauthorUgurlucan, M.
dc.contributor.coauthorSagbas, L. E.
dc.contributor.coauthorAkinci, B.
dc.contributor.departmentKUH (Koç University Hospital)
dc.contributor.kuauthorEzelsoy, Mehmet
dc.contributor.schoolcollegeinstituteKUH (KOÇ UNIVERSITY HOSPITAL)
dc.date.accessioned2026-07-22T13:08:18Z
dc.date.issued2026
dc.description.abstractCardiac surgery may reduce pulmonary function, respiratory muscle strength, and functional capacity after surgery. Respiratory muscle training (RMT) is recommended in cardiac rehabilitation; however, evidence regarding RMT within HCR remains limited. Objective To evaluate the effects of adding RMT to an HCR program following cardiac surgery in a randomized controlled trial. Methods In this randomized controlled trial, 20 patients were randomized to HCR (n = 10) or HCR + RMT (n = 10). Rehabilitation started in postoperative week 1 and continued for 8 weeks. Both groups received HCR, while the HCR + RMT group performed combined inspiratory and expiratory muscle training. Primary outcomes were pulmonary function, respiratory muscle strength, and 6-min walk distance. Secondary outcomes included quality of life, physical activity, usability, feasibility, and satisfaction. Results Twenty participants completed the study, with 100% retention and attendance in both groups and no adverse events. At postoperative week 1, respiratory and functional parameters declined in both groups. By week 8, 6-min walk distance increased by 49.5 m in the HCR group and 55.5 m in the HCR + RMT group. Duke Activity Status Index scores improved by 5.25 and 4.95 points, respectively, while Minnesota Living with Heart Failure Questionnaire scores decreased by 7–9 points. No significant between-group differences were found for any outcome (all p > 0.05). Conclusions Adding RMT to HCR is feasible, safe, and well accepted. Both interventions improved respiratory function, respiratory muscle strength, functional capacity, physical activity, and quality of life. Although no additional short-term benefit was observed with RMT, it may be considered complementary to HCR programs. Clinical trial registration number NCT06258681.
dc.description.harvestedfromManual
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.publisherscopeInternational
dc.description.readpublishN/A
dc.description.sponsoredbyTubitakEuTÜBİTAK
dc.description.sponsorshipThis study was supported by the Scientific and Technological Research Council of Turkiye (TUBITAK) , Project no: 122S643.
dc.description.versionPublished Version
dc.identifier.ScopusPercentile63
dc.identifier.ScopusQuartileQ2
dc.identifier.WoSPercentile66.0
dc.identifier.WoSQuartileQ2
dc.identifier.doi10.1016/j.rmed.2026.109018
dc.identifier.eissn1532-3064
dc.identifier.embargoN/A
dc.identifier.grantno122S643
dc.identifier.issn0954-6111
dc.identifier.pubmed42386010
dc.identifier.scopus2-s2.0-105043481034
dc.identifier.urihttp://doi.org/10.1016/j.rmed.2026.109018
dc.identifier.urihttps://hdl.handle.net/20.500.14288/33761
dc.identifier.volume261
dc.identifier.wos001819881600001
dc.keywordsCardiac surgery
dc.keywordsCoronary artery bypass grafting
dc.keywordsHybrid cardiac rehabilitation
dc.keywordsRespiratory muscle training
dc.keywordsPulmonary function
dc.languageeng
dc.publisherElsevier
dc.relation.affiliationKoç University
dc.relation.collectionKoç University Institutional Repository
dc.relation.ispartofRespiratory Medicine
dc.subjectCardiovascular system and cardiology
dc.subjectRespiratory system
dc.titleEffects of integrated inspiratory–expiratory muscle training within hybrid Cardiac rehabilitation following cardiac surgery: a randomized controlled study
dc.typeJournal Article
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