The role of immature granulocytes and inflammatoryhemogram indices in the inflammation

Abstract

Objectives: In this retrospective study, we aimed to assess the role of immature granulocyte percentage (IG%), inflammatory complete blood count (CBC) parameters and indices in investigating the severity of inflammation, to evaluate their correlation, and to determine their predictive ability in classifying inflammation. Methods: We obtained hematological and biochemical data of the 161 outpatients for this study. Patients were assigned to three groups according to their C-reactive protein (CRP) levels. Group I had a CRp-value of 9mg/L (clinically significant inflammatory group)(n=44). The between-group differences were evaluated concerning sex, age, CRP, procalcitonin, IG%, CBC parameters and indices, including Platelet-to-Lymphocyte Ratio (PLR), Neutrophil-to-Lymphocyte Ratio (NLR) and Systemic Immune-Inflammatory Index (SII). Results: In Group II, the levels of CRP (p0.2 were 75.3% and 52.5%, respectively. Conclusion: The findings obtained in this study suggest that to detect the severity of inflammation, it would be more reliable to evaluate the combination of CBC parameters with biochemical markers instead of looking at a single one.