Publication:
Wireless MRI-powered reversible orientation-locking capsule robot

dc.contributor.coauthorErin, Önder
dc.contributor.coauthorBoyvat, Mustafa
dc.contributor.coauthorLazovic, Jelena
dc.contributor.coauthorTiryaki, Mehmet Efe
dc.contributor.departmentDepartment of Mechanical Engineering
dc.contributor.kuauthorSitti, Metin
dc.contributor.kuprofileFaculty Member
dc.contributor.otherDepartment of Mechanical Engineering
dc.contributor.schoolcollegeinstituteCollege of Engineering
dc.contributor.schoolcollegeinstituteSchool of Medicine
dc.contributor.yokid297104
dc.date.accessioned2024-11-09T13:45:36Z
dc.date.issued2021
dc.description.abstractMagnetic resonance imaging (MRI) scanners do not provide only high-resolution medical imaging but also magnetic robot actuation and tracking. However, the rotational motion capabilities of MRI-powered wireless magnetic capsule-type robots have been limited due to the very high axial magnetic field inside the MRI scanner. Medical functionalities of such robots also remain a challenge due to the miniature robot designs. Therefore, a wireless capsule-type reversible orientation-locking robot (REVOLBOT) is proposed that has decoupled translational motion and planar orientation change capability by locking and unlocking the rotation of a spherical ferrous bead inside the robot on demand. Such an on-demand locking/unlocking mechanism is achieved by a phase-changing wax material in which the ferrous bead is embedded inside. Controlled and on-demand hyperthermia and drug delivery using wireless power transfer-based Joule heating induced by external alternating magnetic fields are the additional features of this robot. The experimental feasibility of the REVOLBOT prototype with steerable navigation, medical function, and MRI tracking capabilities with an 1.33 Hz scan rate is demonstrated inside a preclinical 7T small-animal MRI scanner. The proposed robot has the potential for future clinical use in teleoperated minimally invasive treatment procedures with hyperthermia and drug delivery capabilities while being wirelessly powered and monitored inside MRI scanners.nd. Such an on-demand locking/unlocking mechanism is achieved by a phase-changing wax material in which the ferrous bead is embedded inside. Controlled and on-demand hyperthermia and drug delivery using wireless power transfer-based Joule heating induced by external alternating magnetic fields are the additional features of this robot. The experimental feasibility of the REVOLBOT prototype with steerable navigation, medical function, and MRI tracking capabilities with an 1.33 Hz scan rate is demonstrated inside a preclinical 7T small-animal MRI scanner. The proposed robot has the potential for future clinical use in teleoperated minimally invasive treatment procedures with hyperthermia and drug delivery capabilities while being wirelessly powered and monitored inside MRI scanners.
dc.description.fulltextYES
dc.description.indexedbyWoS
dc.description.indexedbyScopus
dc.description.issue13
dc.description.openaccessYES
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuEU
dc.description.sponsorshipEuropean Union (EU) Horizon 2020
dc.description.sponsorshipEuropean Research Council (ERC) Advanced Grant SoMMoR Project
dc.description.sponsorshipMax Planck Society
dc.description.versionPublisher version
dc.description.volume8
dc.formatpdf
dc.identifier.doi10.1002/advs.202100463
dc.identifier.eissn2198-3844
dc.identifier.embargoNO
dc.identifier.filenameinventorynoIR02950
dc.identifier.linkhttps://doi.org/10.1002/advs.202100463
dc.identifier.quartileQ1
dc.identifier.scopus2-s2.0-85104944366
dc.identifier.urihttps://hdl.handle.net/20.500.14288/3634
dc.identifier.wos646314400001
dc.keywordsMagnetic actuation
dc.keywordsMagnetic resonance imaging
dc.keywordsMedical robots
dc.keywordsMillirobots
dc.keywordsMinimally invasive medical devices
dc.languageEnglish
dc.publisherWiley
dc.relation.grantno834531
dc.relation.urihttp://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/9597
dc.sourceAdvanced Science
dc.subjectChemistry
dc.subjectScience and technology
dc.subjectMaterials science
dc.titleWireless MRI-powered reversible orientation-locking capsule robot
dc.typeJournal Article
dspace.entity.typePublication
local.contributor.authorid0000-0001-8249-3854
local.contributor.kuauthorSitti, Metin
relation.isOrgUnitOfPublicationba2836f3-206d-4724-918c-f598f0086a36
relation.isOrgUnitOfPublication.latestForDiscoveryba2836f3-206d-4724-918c-f598f0086a36

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