Publication:
Diverse clinical signs of ocular involvement in cat scratch disease

dc.contributor.coauthorOray, Merih
dc.contributor.coauthorTutkun, İlknur Tuğal
dc.contributor.departmentKUH (Koç University Hospital)
dc.contributor.departmentSchool of Medicine
dc.contributor.kuauthorAkbay, Aylin Koç
dc.contributor.kuauthorÖnal, Sumru
dc.contributor.schoolcollegeinstituteSCHOOL OF MEDICINE
dc.contributor.schoolcollegeinstituteKUH (KOÇ UNIVERSITY HOSPITAL)
dc.date.accessioned2024-11-09T11:35:36Z
dc.date.issued2017
dc.description.abstractObjectives: To describe ocular manifestations, diagnosis, and treatment of cat scratch disease. Materials and Methods: Clinical records of patients with ocular cat scratch disease were reviewed. Results: Thirteen eyes of 10 patients (7 female, 3 male) with a mean age of 26.9 +/- 18.5 years were included. Nine patients had a history of cat contact and had systemic symptoms associated with cat scratch disease 2-90 days prior to the ocular symptoms. Ocular signs were: neuroretinitis in 4 eyes (associated with serous retinal detachment in the inferior quadrant in 1 eye), optic neuropathy in 2 eyes (1 papillitis and optic disc infiltration, 1 optic neuritis), retinal infiltrates in 6 eyes, retinochoroiditis in 1 eye, branch retinal arteriolar occlusion in 3 eyes, and endophthalmitis in 1 eye. Visual acuities at presentation were 1.0 in 7 eyes, 0.3 in 1 eye, = 0.1 in 4 eyes, and light perception in 1 eye. Bartonella henselae immunoglobulin (Ig) M and/or IgG were positive in all patients. Systemic antibiotic therapy was administered in all patients. Systemic corticosteroid treatment (15-40 mg/day) was added to the therapy in 4 patients, following 5 days of intravenous pulse methylprednisolone in 2 patients. Treatment was ongoing for 1 patient and the mean treatment duration of the other 9 patients was 47 +/- 14.5 days. Visual acuities at final visit were 1.0 in 9 eyes, 0.8 in 1 eye, 0.4 in 1 eye, and no light perception in 1 eye. Conclusion: Cat scratch disease may present with different ocular signs and should be considered in the differential diagnosis in patients with such presentations. / Amaç: Kedi tırmığı hastalığı oküler tutulumu olan hastaların klinik bulguları, tanı ve tedavi yaklaşımlarının değerlendirilmesidir. Gereç ve Yöntem: Kedi tırmığı hastalığına bağlı oküler tutulumu olan olguların klinik kayıtları incelendi. Bulgular: Çalışmaya yaş ortalaması 26,9±18,5 yıl olan 10 hastanın (7 kadın, 3 erkek) 13 gözü dahil edildi. Dokuz hastada kedi teması hikayesi olup hastaların göz şikayetleri başlamadan 2-90 gün önce kedi tırmığı hastalığı ile ilişkili sistemik semptomları vardı. Klinik bulgular, 4 gözde nöroretinit (1 gözde alt periferde seröz retina dekolmanı eşlik etmekte), 2 gözde optik nöropati (1 papillit ve optic disk infiltrasyonu, 1 optik nörit), 6 gözde retinal infiltratlar, 1 gözde retinokoroidit ve 3 gözde retinal arter dal tıkanıklığı, 1 gözde endoftalmi şeklindeydi. Başvuru anında görme keskinliği 7 gözde 1,0, 1 gözde 0,3, 4 gözde ≤0,1 ve 1 gözde ışık hissi düzeyindeydi. Tüm hastalarda Bartonella henselae immünoglobülin (Ig) M ve/veya IgG pozitif idi. Tüm hastalara antibiyotik tedavisi uygulandı. İki hastaya 5 gün pulse metilprednizolon intravenöz tedaviyi takiben ve 4 hastaya 15-40 mg/gün dozunda oral kortikosteroid tedavisi de eklendi. Bir hastanın tedavisi devam etmekte ve kalan 9 hastanın ortalama toplam tedavi süresi 47±14,5 gündü. Son vizitte görme keskinliği 9 gözde 1,0, 1 gözde 0,8, 1 gözde 0,4 ve 1 gözde ışık negatifti.Sonuç: Kedi tırmığı hastalığı farklı oküler tutulum bulguları ile karşımıza çıkabilen ve bu tablolarda ayırıcı tanıda akılda bulundurulması gereken bir hastalıktır.
dc.description.fulltextYES
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.issue1
dc.description.openaccessYES
dc.description.publisherscopeNational
dc.description.sponsoredbyTubitakEuN/A
dc.description.sponsorshipN/A
dc.description.versionPublisher version
dc.description.volume47
dc.identifier.doi10.4274/tjo.28009
dc.identifier.eissn2149-8709
dc.identifier.embargoNO
dc.identifier.filenameinventorynoIR01311
dc.identifier.issn2149-8695
dc.identifier.quartileN/A
dc.identifier.scopus2-s2.0-85011002386
dc.identifier.urihttps://doi.org/10.4274/tjo.28009
dc.identifier.wos397190800004
dc.keywordsCat scratch disease
dc.keywordsNeuroretinitis
dc.keywordsRetinal infiltrate
dc.keywordsOptic neuropathy
dc.keywordsEndophthalmitis
dc.language.isoeng
dc.publisherTürk Oftalmoloji Derneği
dc.relation.ispartofTürk Oftalmoloji Dergisi
dc.relation.urihttp://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/3042
dc.subjectMedicine
dc.subjectOphthalmology
dc.titleDiverse clinical signs of ocular involvement in cat scratch disease
dc.title.alternativeKedi tırmığı hastalığı göz tutulumunda çeşitli klinik bulgular
dc.typeJournal Article
dspace.entity.typePublication
local.contributor.kuauthorÖnal, Sumru
local.contributor.kuauthorAkbay, Aylin Koç
local.publication.orgunit1SCHOOL OF MEDICINE
local.publication.orgunit1KUH (KOÇ UNIVERSITY HOSPITAL)
local.publication.orgunit2KUH (Koç University Hospital)
local.publication.orgunit2School of Medicine
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