Publication: Successful treatment with anakinra in generalized spiculated porokeratosis and severe hidradenitis suppurativa in a patient with MVK and MEFV mutations
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Oktem, Ayse
Cavdarli, Busra
Bostanci, Seher
Heper, Aylin
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Abstract
The synergistic effect of two mutations of the innate immune system may facilitate hyperactivation and dysregulation of the inflammasome in skin macrophages. This case connects two diseases, hidradenitis suppurativa and porokeratosis, by the central role of autoinflammation.
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Oxford University Press
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Clinical and experimental dermatology
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DOI
10.1093/ced/llac023
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