Publication:
Intraocular lens simulator using computational holographic display for cataract patients

dc.contributor.departmentDepartment of Electrical and Electronics Engineering
dc.contributor.departmentGraduate School of Sciences and Engineering
dc.contributor.departmentSchool of Medicine
dc.contributor.kuauthorAkyazı, Deniz
dc.contributor.kuauthorAygün, Uğur
dc.contributor.kuauthorŞahin, Afsun
dc.contributor.kuauthorÜrey, Hakan
dc.contributor.schoolcollegeinstituteCollege of Engineering
dc.contributor.schoolcollegeinstituteGRADUATE SCHOOL OF SCIENCES AND ENGINEERING
dc.contributor.schoolcollegeinstituteSCHOOL OF MEDICINE
dc.date.accessioned2025-03-06T21:00:01Z
dc.date.issued2024
dc.description.abstractPurpose To develop and validate a holography based vision simulator for the demonstration of expected postoperative vision corresponding to monofocal and multifocal intraocular lenses (IOL) to cataract patients before surgery.Methods An artificial eye model is used to measure the optical performance of different IOL types. The resultant aberrations and degradations are then modeled using phase holograms and shown to subjects on a holographic display. We measure the contrast and resolution loss, halos around the light sources, and point spread function (PSF) corresponding to three different IOLs. We tested the holography based vision simulator on 13 healthy subjects and 6 cataract patients.Results Monofocal, bifocal, and trifocal IOLs exhibited a contrast decrease of 5%, 42%, and 45% and a resolution limit of 4.49, 4.00, and 4.00 lp/mm (using 0.05 MTF criteria), respectively. Monofocal IOLs have the best resolution and contrast at the optimal focus distance, and multifocal lenses offer extended depth-of-field but exhibit prominent halos and reduced contrast/resolution.Conclusion We confirmed that the visual functions of IOLs could be successfully modeled using phase holograms and simulated using a holographic display without using a physical IOL. Patients can experience the effects of different IOL options prior to surgery, which helps with IOL selection, expectation management, and patient satisfaction.
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuTÜBİTAK
dc.description.sponsorshipHU. Grant agreement number 120C145, TURKIYE BILIMSEL VE TEKNOLOJIK ARASTIRMA KURUMU. https://www.TÜBİTAK.gov.tr/ HU. AS. Grant agreement no 101057672, European Innovation Council. https://eic.ec.europa.eu/ The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
dc.identifier.doi10.1371/journal.pone.0295215
dc.identifier.grantnoTURKIYE BILIMSEL VE TEKNOLOJIK ARASTIRMA KURUMU [120C145];European Innovation Council [101057672]
dc.identifier.issn1932-6203
dc.identifier.issue10
dc.identifier.quartileQ1
dc.identifier.scopus2-s2.0-85207442738
dc.identifier.urihttps://doi.org/10.1371/journal.pone.0295215
dc.identifier.urihttps://hdl.handle.net/20.500.14288/27830
dc.identifier.volume19
dc.identifier.wos1345720700062
dc.keywordsIntraocular lens (IOL)
dc.keywordsComputational holography
dc.keywordsHolographic display
dc.keywordsCataract patients
dc.keywordsVision simulation
dc.keywordsOptical modeling
dc.keywordsAugmented reality
dc.keywordsMedical imaging
dc.keywordsOphthalmology
dc.keywordsVisual perception
dc.language.isoeng
dc.publisherPublic Library of Science
dc.relation.ispartofPlos One
dc.subjectMultidisciplinary sciences
dc.titleIntraocular lens simulator using computational holographic display for cataract patients
dc.typeJournal Article
dspace.entity.typePublication
local.publication.orgunit1GRADUATE SCHOOL OF SCIENCES AND ENGINEERING
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