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Simulation of temporal stochastic phenomena in electronic and biological systems: a comparative review, examples and synergies

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We concentrate on the temporal stochastic behavior of electronic and biological systems due to mainly intrinsic noise and fluctuation phenomena as opposed to extrinsic crosstalk-like interference or statistical variations in system parameters. We provide an overview of modeling and analysis techniques for noise and fluctuation phenomena in biological systems with comparisons to electronic systems. We present several examples where a synergistic cross-fertilization between the two disciplines seems promising. In particular, we discuss the characterization of conformational fluctuations in proteins, the simulation of stochastic behavior in intracellular processes, and the modeling of noise in biological neurons, neuronal networks, nervous system and the brain.

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Institute of Electrical and Electronics Engineers (IEEE)
IEEE Council on Electronic Design Automation (CEDA)
Association for Computing Machinery, Special
Interest Group on Design Automation (ACM SIGDA)

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IEEE/ACM International Conference on Computer-Aided Design, Digest of Technical Papers, ICCAD

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10.1109/ICCAD.2013.6691206

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