Publication: A brand-new cardiorenal syndrome in the Coronavirus Disease- 2019 (COVID-19) setting
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Program
KU-Authors
KU Authors
Co-Authors
Apetrii, Mugurel
Enache, Stefana
Siriopol, Dimitrie
Burlacu, Alexandru
Kanbay, Asiye
Scripcariu, Dragos
Covic, Adrian
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NO
Journal Title
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Abstract
Coronaviruses are a major pathogen for adults, causing up to one-third of community-acquired respiratory tract infections in adults during epidemics. Although the pandemic outbreak of coronavirus disease-2019 (COVID-19) targets preferentially patient’s lungs, recent data have documented that COVID-19 causes myocarditis, acute myocardial infarction, exacerbation of heart failure and acute kidney injury. Studies show that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), similar to its predecessor SARS-CoV, engages angiotensin-converting enzyme 2 (ACE2) as the entry receptor. ACE2 is also expressed in the heart, providing a link between coronaviruses and the cardiovascular system.
Source
Publisher
Oxford University Press (OUP)
Subject
Medicine
Citation
Has Part
Source
Clinical Kidney Journal
Book Series Title
Edition
DOI
10.1093/ckj/sfaa082