Publication:
Effects of antenatal magnesium exposure on intestinal blood flow and outcome in Preterm Neonates

dc.contributor.coauthorİmamoğlu, Ebru Yalın
dc.contributor.coauthorOvalı, Fahri
dc.contributor.coauthorKaratekin, Güner
dc.contributor.departmentN/A
dc.contributor.kuauthorGürsoy, Tuğba
dc.contributor.kuprofileFaculty Member
dc.contributor.schoolcollegeinstituteSchool of Medicine
dc.contributor.yokid214691
dc.date.accessioned2024-11-09T13:46:45Z
dc.date.issued2015
dc.description.abstractObjective This study aims to investigate the effects of antenatal magnesium sulfate on intestinal blood flow in preterm neonates. Study Design In this prospective case-match study, 25 preterm neonates exposed to magnesium sulfate antenatally were included (study group). Overall, 25 gestational age-matched neonates who had no exposure to magnesium constituted the control group. Serial daily Doppler flow measurements of superior mesenteric artery (SMA) were performed. The time to reach full feeds, first meconium passage were assessed. Presence of feeding intolerance or necrotizing enterocolitis was recorded. Results Blood flow velocities of SMA were not different between the groups during the first five postnatal days. However, SMA blood flow showed an increasing trend in the control group unlike the study group (control group, p < 0.001; study group, p = 0.29). There was no significant difference between the two groups regarding the time to reach full feeds or first meconium passage and presence of feeding intolerance. No case of necrotizing enterocolitis was seen. Conclusion Antenatal magnesium does not significantly affect intestinal blood flow, but it seems to attenuate the increasing trend of the intestinal blood flow in the early postnatal days. However, this study failed to show any impact of this finding on clinical outcomes.
dc.description.fulltextYES
dc.description.indexedbyWoS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.issue11
dc.description.openaccessYES
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuN/A
dc.description.sponsorshipN/A
dc.description.versionPublisher version
dc.description.volume32
dc.formatpdf
dc.identifier.doi10.1055/s-0035-1548541
dc.identifier.eissn1098-8785
dc.identifier.embargoNO
dc.identifier.filenameinventorynoIR00366
dc.identifier.issn0735-1631
dc.identifier.linkhttps://doi.org/10.1055/s-0035-1548541
dc.identifier.quartileQ3
dc.identifier.scopus2-s2.0-84941598877
dc.identifier.urihttps://hdl.handle.net/20.500.14288/3724
dc.identifier.wos361410300010
dc.keywordsSuperior mesenteric-artery
dc.keywordsDuctus-arteriosus
dc.keywordsPremature-infants
dc.keywordsControlled-trial
dc.keywords1st stool
dc.keywordsSulfate
dc.keywordsVelocity
dc.keywordsPregnancy
dc.keywordsHypertension
dc.keywordsRisk
dc.languageEnglish
dc.publisherThieme Medical Publishers
dc.relation.urihttp://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/1387
dc.sourceAmerican Journal of Perinatology
dc.subjectMedicine
dc.subjectObstetrics and gynecology
dc.subjectPediatrics
dc.titleEffects of antenatal magnesium exposure on intestinal blood flow and outcome in Preterm Neonates
dc.typeJournal Article
dspace.entity.typePublication
local.contributor.authorid0000-0002-6084-4067
local.contributor.kuauthorGürsoy, Tuğba

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