Publication: Early use of ribavirin is beneficial in Crimean-Congo hemorrhagic fever
Program
KU-Authors
KU Authors
Co-Authors
Özbey, Saliha Bakır
Kader, Çiğdem
Erbay, Ayşe
Advisor
Publication Date
2014
Language
English
Type
Journal Article
Journal Title
Journal ISSN
Volume Title
Abstract
We evaluated the effect of early use of ribavirin on outcomes of patients at a secondary care hospital. The study included patients who were hospitalized between 2005 and 2010 at the Infectious Diseases Department of Kastamonu Dr. Munif Islamoglu Hospital in the Kastamonu Province of Turkey. In total, 342 confirmed cases of Crimean-Congo hemorrhagic fever (CCHF) were included in the study. The overall case fatality rate was 2.9%. In multivariate analysis, the patients that were admitted to the hospital within 2 days after onset of symptoms (odds ratio [OR] = 5, confidence interval [CI] 0.31-0.86) and received oral ribavirin (OR = 0.12, CI 0.05-0.26) were less likely to become more severe cases and less likely to be transferred to the tertiary care centers. Having vaginal bleeding was a significant parameter for transfer.
Description
Source:
Vector-Borne and Zoonotic Diseases
Publisher:
Mary Ann Liebert, Inc
Keywords:
Subject
Public, environmental and occupational health, Infectious diseases