Publication:
Vein of galen malformations: for patients and caregivers

dc.contributor.coauthorDarko, Kwadwo
dc.contributor.coauthorDetchou, Donald
dc.contributor.coauthorBarrie, Umaru
dc.contributor.departmentSchool of Medicine
dc.contributor.kuauthorAydın, Serhat
dc.contributor.schoolcollegeinstituteSCHOOL OF MEDICINE
dc.date.accessioned2025-03-06T20:59:47Z
dc.date.issued2024
dc.description.abstractVein of Galen malformations (VOGMs), also known as Vein of Galen Aneurysmal Malformations (VGAMs), are rare and complex cerebrovascular anomalies that pose significant diagnostic and therapeutic challenges. These malformations result from abnormal arteriovenous shunts during embryonic development, leading to a range of severe clinical manifestations, including high-output cardiac failure and hydrocephalus. Advances in prenatal imaging, particularly fetal MRI, have improved early detection, allowing for timely intervention. Endovascular techniques, especially transarterial embolization, have become the primary treatment modality, often preferred over surgical approaches due to their effectiveness and lower risk. However, challenges remain, particularly in managing these malformations in neonates and infants, where the risk of complications is high. Gamma Knife radiosurgery offers a non-invasive alternative for select cases, though its effects are gradual and may carry delayed risks. Despite advancements, the management of VOGMs continues to require a multidisciplinary approach, with ongoing research focused on improving outcomes through a better understanding of the genetic and molecular underpinnings of the disease. Future directions include the integration of genetic studies into clinical practice and the refinement of treatment strategies to optimize outcomes for this complex condition.
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuN/A
dc.identifier.doi10.1007/s10143-024-02851-w
dc.identifier.eissn1437-2320
dc.identifier.issn0344-5607
dc.identifier.issue1
dc.identifier.quartileQ1
dc.identifier.scopus2-s2.0-85203672335
dc.identifier.urihttps://doi.org/10.1007/s10143-024-02851-w
dc.identifier.urihttps://hdl.handle.net/20.500.14288/27772
dc.identifier.volume47
dc.identifier.wos1310067700004
dc.keywordsVein
dc.keywordsGalen
dc.keywordsMalformations
dc.keywordsGamma Knife
dc.keywordsRadiosurgery
dc.language.isoeng
dc.publisherSpringer
dc.relation.ispartofNeurosurgical Review
dc.subjectClinical neurology
dc.subjectSurgery
dc.titleVein of galen malformations: for patients and caregivers
dc.typeLetter
dspace.entity.typePublication
local.contributor.kuauthorAydın, Serhat
local.publication.orgunit1SCHOOL OF MEDICINE
local.publication.orgunit2School of Medicine
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relation.isParentOrgUnitOfPublication.latestForDiscovery17f2dc8e-6e54-4fa8-b5e0-d6415123a93e

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