Publication:
Impact of spinal manipulation on cortical drive to upper and lower limb muscles

dc.contributor.coauthorHaavik Heidi
dc.contributor.coauthorNiazi, Imran Khan
dc.contributor.coauthorJochumsen, Mads
dc.contributor.coauthorSherwin, Diane
dc.contributor.coauthorFlavel, Stanley
dc.contributor.departmentSchool of Medicine
dc.contributor.kuauthorTürker, Kemal Sıtkı
dc.contributor.schoolcollegeinstituteSCHOOL OF MEDICINE
dc.date.accessioned2024-11-09T11:49:42Z
dc.date.issued2017
dc.description.abstractThis study investigates whether spinal manipulation leads to changes in motor control by measuring the recruitment pattern of motor units in both an upper and lower limb muscle and to see whether such changes may at least in part occur at the cortical level by recording movement related cortical potential (MRCP) amplitudes. In experiment one, transcranial magnetic stimulation input-output (TMS I/O) curves for an upper limb muscle (abductor pollicus brevis; APB) were recorded, along with F waves before and after either spinal manipulation or a control intervention for the same subjects on two different days. During two separate days, lower limb TMS I/O curves and MRCPs were recorded from tibialis anterior muscle (TA) pre and post spinal manipulation. Dependent measures were compared with repeated measures analysis of variance, with p set at 0.05. Spinal manipulation resulted in a 54.5% +/- 93.1% increase in maximum motor evoked potential (MEPmax) for APB and a 44.6% +/- 69.6% increase in MEPmax for TA. For the MRCP data following spinal manipulation there were significant difference for amplitude of early bereitschafts-potential (EBP), late bereitschafts potential (LBP) and also for peak negativity (PN). The results of this study show that spinal manipulation leads to changes in cortical excitability, as measured by significantly larger MEPmax for TMS induced input-output curves for both an upper and lower limb muscle, and with larger amplitudes of MRCP component post manipulation. No changes in spinal measures (i.e., F wave amplitudes or persistence) were observed, and no changes were shown following the control condition. These results are consistent with previous findings that have suggested increases in strength following spinal manipulation were due to descending cortical drive and could not be explained by changes at the level of the spinal cord. Spinal manipulation may therefore be indicated for the patients who have lost tonus of their muscle and/or are recovering from muscle degrading dysfunctions such as stroke or orthopaedic operations and/or may also be of interest to sports performers. These findings should be followed up in the relevant populations.
dc.description.fulltextYES
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.issue1
dc.description.openaccessYES
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuN/A
dc.description.sponsorshipAustralian Spinal Research Foundation
dc.description.sponsorshipHamblin Chiropractic Research Fund Trust
dc.description.sponsorshipNew Zealand College of Chiropractic
dc.description.sponsorshipKoç University
dc.description.versionPublisher version
dc.description.volume7
dc.identifier.doi10.3390/brainsci7010002
dc.identifier.embargoNO
dc.identifier.filenameinventorynoIR00482
dc.identifier.quartileQ3
dc.identifier.scopus2-s2.0-85009769768
dc.identifier.urihttps://hdl.handle.net/20.500.14288/653
dc.identifier.wos395483700002
dc.keywordsTranscranial magnetic stimulation
dc.keywordsMovement related cortical potential
dc.keywordsNeural adaptations
dc.keywordsSubclinical neck pain
dc.keywordsSomatosensory-evoked-potentials
dc.keywordsVoluntary finger movement
dc.keywordsSupplementary motor area
dc.keywordsInput-output properties
dc.keywordsLow-back-pain
dc.keywordsCervical-spine
dc.keywordsSensorimotor integration
dc.language.isoeng
dc.publisherMultidisciplinary Digital Publishing Institute (MDPI)
dc.relation.ispartofBrain Sciences
dc.relation.urihttp://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/552
dc.subjectMedicine
dc.subjectNeurosciences and neurology
dc.titleImpact of spinal manipulation on cortical drive to upper and lower limb muscles
dc.typeJournal Article
dspace.entity.typePublication
local.contributor.kuauthorTürker, Kemal Sıtkı
local.publication.orgunit1SCHOOL OF MEDICINE
local.publication.orgunit2School of Medicine
relation.isOrgUnitOfPublicationd02929e1-2a70-44f0-ae17-7819f587bedd
relation.isOrgUnitOfPublication.latestForDiscoveryd02929e1-2a70-44f0-ae17-7819f587bedd
relation.isParentOrgUnitOfPublication17f2dc8e-6e54-4fa8-b5e0-d6415123a93e
relation.isParentOrgUnitOfPublication.latestForDiscovery17f2dc8e-6e54-4fa8-b5e0-d6415123a93e

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
552.pdf
Size:
460.32 KB
Format:
Adobe Portable Document Format