Publication:
Effect of the endometrial thickness on the live birth rate: insights from 959 single euploid frozen embryo transfers without a cutoff for thickness

dc.contributor.coauthorLiñán, Alberto
dc.contributor.coauthorRuíz, Francisco
dc.contributor.coauthorMelado, Laura
dc.contributor.coauthorBayram, Asina
dc.contributor.coauthorElkhatib, Ibrahim
dc.contributor.coauthorLawrenz, Barbara
dc.contributor.coauthorFatemi, Human M.
dc.contributor.departmentSchool of Medicine
dc.contributor.kuauthorAta, Mustafa Barış
dc.contributor.kuauthorKalafat, Erkan
dc.contributor.schoolcollegeinstituteSCHOOL OF MEDICINE
dc.date.accessioned2024-11-09T23:29:50Z
dc.date.issued2023
dc.description.abstractObjective: to investigate whether endometrial thickness (ET) independently affects the live birth rate (LBR) after embryo transfer. Design: retrospective study. Setting: private assisted reproductive technology center. Patient(s): a total of 959 single euploid frozen embryo transfers. Intervention(s): vitrified euploid blastocyst transfer. Main outcome measure(s): live birth rate per embryo transfer. Result(s): the conditional density plots did not demonstrate either a linear relationship between the ET and LBR or a threshold below which the LBR decreased perceivably. Receiver operating characteristic curve analyses did not suggest a predictive value of the ET for the LBR. The area under the curve values were 0.55, 0.54, and 0.54 in the overall, programmed, and natural cycle transfers, respectively. Logistic regression analyses with age, embryo quality, day of trophectoderm biopsy, body mass index, and ET did not suggest an independent effect of the ET on the LBR. Conclusion(s): we did not identify a threshold of the ET that either precluded live birth or under which the LBR decreases perceivably. Common practice of cancelling embryo transfers when the ET is <7 mm may not be justified. Prospective studies, in which the management of the transfer cycle would not be altered by ET, would provide higher-quality evidence on the subject.
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.issue1
dc.description.openaccessNO
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuN/A
dc.description.volume120
dc.identifier.doi10.1016/j.fertnstert.2023.02.035
dc.identifier.eissn1556-5653
dc.identifier.issn0015-0282
dc.identifier.quartileQ1
dc.identifier.scopus2-s2.0-85159330597
dc.identifier.urihttps://doi.org/10.1016/j.fertnstert.2023.02.035
dc.identifier.urihttps://hdl.handle.net/20.500.14288/12133
dc.identifier.wos1025828900001
dc.keywordsIn vitro fertilization
dc.keywordsEndometrial thickness
dc.keywordsFrozen embryo transfer
dc.keywordsLive birth
dc.keywordsPreimplantation genetic testing
dc.language.isoeng
dc.publisherElsevier
dc.relation.ispartofFertil Steril
dc.subjectReproductive medicine
dc.subjectFertility
dc.subjectInfertility
dc.titleEffect of the endometrial thickness on the live birth rate: insights from 959 single euploid frozen embryo transfers without a cutoff for thickness
dc.typeJournal Article
dspace.entity.typePublication
local.contributor.kuauthorAta, Mustafa Barış
local.contributor.kuauthorKalafat, Erkan
local.publication.orgunit1SCHOOL OF MEDICINE
local.publication.orgunit2School of Medicine
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