Publication:
Dynamics of pattern formation and emergence of swarming in Caenorhabditis elegans

dc.contributor.departmentDepartment of Physics
dc.contributor.departmentGraduate School of Sciences and Engineering
dc.contributor.departmentKUTTAM (Koç University Research Center for Translational Medicine)
dc.contributor.departmentKUYTAM (Koç University Surface Science and Technology Center)
dc.contributor.kuauthorBaşaran, Mustafa
dc.contributor.kuauthorDemir, Esin
dc.contributor.kuauthorKocabaş, Aşkın
dc.contributor.kuauthorYaman, Yusuf İlker
dc.contributor.schoolcollegeinstituteCollege of Sciences
dc.contributor.schoolcollegeinstituteGRADUATE SCHOOL OF SCIENCES AND ENGINEERING
dc.contributor.schoolcollegeinstituteResearch Center
dc.date.accessioned2024-11-09T12:46:04Z
dc.date.issued2020
dc.description.abstractMany animals collectively form complex patterns to tackle environmental difficulties. Several biological and physical factors, such as animal motility, population densities, and chemical cues, play significant roles in this process. However, very little is known about how sensory information interplays with these factors and controls the dynamics of pattern formation. Here, we study the direct relation between oxygen sensing, pattern formation, and emergence of swarming in active Caenorhabditis elegans aggregates. We find that when thousands of animals gather on food, bacteria-mediated decrease in oxygen level slows down the animals and triggers motility-induced phase separation. Three coupled factors-bacterial accumulation, aerotaxis, and population density-act together and control the entire dynamics. Furthermore, we find that biofilm-forming bacterial lawns including Bacillus subtilis and Pseudomonas aeruginosa strongly alter the collective dynamics due to the limited diffusibility of bacteria. Additionally, our theoretical model captures behavioral differences resulting from genetic variations and oxygen sensitivity.
dc.description.fulltextYES
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.openaccessYES
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuTÜBİTAK
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TÜBİTAK)
dc.description.sponsorshipESRC Research Centre on Micro-Social Change at the University of Essex
dc.description.sponsorshipTurkish Academy of the Sciences (Turkish Academy of Sciences (TÜBA)-GEBIP grant)
dc.description.sponsorshipScience Academy (BAGEP grant)
dc.description.sponsorshipBritish Academy
dc.description.versionPublisher version
dc.description.volume9
dc.identifier.doi10.7554/eLife.52781
dc.identifier.embargoNO
dc.identifier.filenameinventorynoIR02170
dc.identifier.issn2050-084X
dc.identifier.quartileQ1
dc.identifier.scopus2-s2.0-85084345766
dc.identifier.urihttps://hdl.handle.net/20.500.14288/2463
dc.identifier.wos531829300001
dc.keywordsCollective behavior
dc.keywordsNatural variation
dc.keywordsSocial-behavior
dc.keywordsCircuit
dc.keywordsNeurons
dc.keywordsAggregation
dc.keywordsPathways
dc.keywordsDriven
dc.language.isoeng
dc.publishereLife Sciences Publications
dc.relation.grantno115F072 and 115S666
dc.relation.grantnoIG 3275
dc.relation.ispartofeLife
dc.relation.urihttp://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/8815
dc.subjectLife sciences and biomedicine
dc.titleDynamics of pattern formation and emergence of swarming in Caenorhabditis elegans
dc.typeJournal Article
dspace.entity.typePublication
local.contributor.kuauthorDemir, Esin
local.contributor.kuauthorBaşaran, Mustafa
local.contributor.kuauthorYaman, Yusuf İlker
local.contributor.kuauthorKocabaş, Aşkın
local.publication.orgunit1GRADUATE SCHOOL OF SCIENCES AND ENGINEERING
local.publication.orgunit1College of Sciences
local.publication.orgunit1Research Center
local.publication.orgunit2KUYTAM (Koç University Surface Science and Technology Center)
local.publication.orgunit2KUTTAM (Koç University Research Center for Translational Medicine)
local.publication.orgunit2Department of Physics
local.publication.orgunit2Graduate School of Sciences and Engineering
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