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Modeling and analysis of the cross-talk regulators between the AKT and ERK signaling pathways

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The cross-talk between different signal transduction pathways plays a key role in the regulation of cellular functions. This paper models the major feedback loops involved in the cross-talk between AKT and ERK signaling pathways. The developed models can be used to improve our understanding of the complex interactions between two important pathways at the systems level.

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Elsevier

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Science and technology, Chemical and biological engineering

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IFAC-PapersOnLine

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10.1016/j.ifacol.2019.06.115

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