Publication: A novel method for PEGylation of chitosan nanoparticles through photopolymerization
Files
Program
KU Authors
Co-Authors
Publication Date
Language
Type
Embargo Status
NO
Journal Title
Journal ISSN
Volume Title
Alternative Title
Abstract
An ultrafast and convenient method for PEGylation of chitosan nanoparticles has been established through a photopolymerization reaction between the acrylate groups of PEG and methacrylated-chitosan nanoparticles. The nanoparticle characteristics under physiological pH conditions were optimized through altered PEG chain length, concentration and duration of UV exposure. The method developed here has potential for clinical translation of chitosan nanoparticles. It also allows for the scalable and fast synthesis of nanoparticles with colloidal stability.
Source
Publisher
Royal Society of Chemistry (RSC)
Subject
Chemistry
Citation
Has Part
Source
RSC Advances