Publication:
Exercise capacity in axial spondyloarthritis and associated factors: a cross-sectional controlled study

dc.contributor.coauthorTohma, Ebru Köseoğlu
dc.contributor.coauthorGünendi, Zafer
dc.contributor.coauthorMengi, Gönen
dc.contributor.coauthorDemirsoy, Nesrin
dc.contributor.coauthorTaş, Nihal
dc.contributor.departmentSchool of Medicine
dc.contributor.kuauthorTaşkıran, Özden Özyemişçi
dc.contributor.schoolcollegeinstituteSCHOOL OF MEDICINE
dc.date.accessioned2024-11-10T00:01:34Z
dc.date.issued2021
dc.description.abstractObjective To examine the associations between exercise capacity (EC), cardiovascular (CV) risk factors and disease-related variables in axial spondyloarthritis (AxSpA) patients. Methods In this cross-sectional controlled study, CV risk profile data, physical activity, 10-year CV event risk estimated by the Framingham model and Ankylosing Spondylitis Disease Activity Score - C-reactive protein were recorded. A maximal treadmill exercise test by Bruce protocol was administered. Analyses of covariance were performed with adjustments for age, smoking status and physical activity level. Linear regression analysis was performed to study the association between EC and related CV risk factors. Results Thirty-eight patients and 38 age-gender matched controls were recruited between May and October 2014. Patients had significantly lower EC than controls (MD 2.2; metabolic equivalents 0.91-3.49; P = .001). The difference remained significant after adjustments (P = .001). There were significant correlations between EC and age, 10-year CV event risk, body mass index (BMI) and waist circumference for patients and controls (P P < .05, respectively). There was a significant relationship between EC and total cholesterol, triglycerides and heart rate recovery (HRR) in patients (P = .04, P P = .006, respectively). High-density lipoprotein - cholesterol was significantly higher, and BMI was significantly lower in nonradiographic AxSpA patients (P = .026 and P = .03 respectively). Age and triglyceride levels were found as the significant predictors for EC in the AxSpa group (for age beta = -.105, P = .003; for triglycerides beta = -.016 P = .003). Conclusion Exercise capacity was significantly lower and attenuated HRR was significantly associated with low EC and high 10-year CV event risk in AxSpA patients.
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.issue8
dc.description.openaccessNO
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuN/A
dc.description.volume24
dc.identifier.doi10.1111/1756-185X.14155
dc.identifier.eissn1756-185X
dc.identifier.issn1756-1841
dc.identifier.quartileQ3
dc.identifier.scopus2-s2.0-85107948607
dc.identifier.urihttps://doi.org/10.1111/1756-185X.14155
dc.identifier.urihttps://hdl.handle.net/20.500.14288/15984
dc.identifier.wos661874500001
dc.keywordsAnkylosing spondylitis
dc.keywordsAxial spondyloarthritis
dc.keywordsCardiovascular risk factors
dc.keywordsExercise capacity
dc.keywordsPhysical activity
dc.language.isoeng
dc.publisherWiley
dc.relation.ispartofInternational Journal of Rheumatic Diseases
dc.subjectRheumatology
dc.titleExercise capacity in axial spondyloarthritis and associated factors: a cross-sectional controlled study
dc.typeJournal Article
dspace.entity.typePublication
local.contributor.kuauthorTaşkıran, Özden Özyemişçi
local.publication.orgunit1SCHOOL OF MEDICINE
local.publication.orgunit2School of Medicine
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relation.isParentOrgUnitOfPublication17f2dc8e-6e54-4fa8-b5e0-d6415123a93e
relation.isParentOrgUnitOfPublication.latestForDiscovery17f2dc8e-6e54-4fa8-b5e0-d6415123a93e

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