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The role of uric acid in the acute myocardial infarction: a narrative review

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dc.contributor.coauthorAfsar, Baris
dc.contributor.coauthorCovic, Adrian
dc.contributor.coauthorKuwabara, Masanari
dc.contributor.coauthorFerro, Charles J.
dc.contributor.coauthorLanaspa, Miguel A.
dc.contributor.coauthorJohnson, Richard J.
dc.contributor.departmentSchool of Medicine
dc.contributor.kuauthorDemiray, Atalay
dc.contributor.kuauthorKanbay, Mehmet
dc.contributor.schoolcollegeinstituteSCHOOL OF MEDICINE
dc.date.accessioned2024-11-09T23:14:46Z
dc.date.issued2022
dc.description.abstractIncreased serum uric acid (SUA) levels have been associated with various pathologic processes such as increased oxidative stress, inflammation, and endothelial dysfunction. Thus, it is not surprising that increased SUA is associated with various adverse outcomes including cardiovascular (CV) diseases. Recent epidemiological evidence suggests that increased SUA may be related to acute myocardial infarction (AMI). Accumulating data also showed that elevated UA has pathophysiological role in the development of AMI. However, there are also studies showing that SUA is not related to the risk of AMI. In this narrative review, we summarized the recent literature data regarding SUA and AMI after providing some background information for the association between UA and coronary artery disease. Future studies will show whether decreasing SUA levels is beneficial for outcomes related to AMI and the optimum SUA levels for best outcomes in CV diseases.
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.issue1
dc.description.openaccessNO
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuN/A
dc.description.sponsorshipPresidency of Turkey
dc.description.sponsorshipPresidency of Strategy and Budget MK gratefully thanks the use of the services and facilities of the Koc University Research Center for Translational Medicine (KUTTAM), funded by the Presidency of Turkey, Presidency of Strategy and Budget.
dc.description.volume73
dc.identifier.doi10.1177/00033197211012546
dc.identifier.eissn1940-1574
dc.identifier.issn0003-3197
dc.identifier.quartileQ3
dc.identifier.scopus2-s2.0-85105068614
dc.identifier.urihttps://doi.org/10.1177/00033197211012546
dc.identifier.urihttps://hdl.handle.net/20.500.14288/10211
dc.identifier.wos648416000001
dc.keywordsUric acid
dc.keywordsCoronary artery disease
dc.keywordsInflammation
dc.keywordsKidney disease
dc.keywordsMyocardial infarction
dc.language.isoeng
dc.publisherSage
dc.relation.ispartofAngiology
dc.subjectPeripheral vascular disease
dc.subjectCardiovascular system
dc.subjectCardiology
dc.titleThe role of uric acid in the acute myocardial infarction: a narrative review
dc.typeReview
dspace.entity.typePublication
local.contributor.kuauthorDemiray, Atalay
local.contributor.kuauthorKanbay, Mehmet
local.publication.orgunit1SCHOOL OF MEDICINE
local.publication.orgunit2School of Medicine
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