Publication:
Does submandibular gland sacrificing neck dissection decrease salivary output and quality of life?

dc.contributor.coauthorOzer, Furkan
dc.contributor.coauthorKuscu, Oguz
dc.contributor.coauthorSuslu, Nilda
dc.contributor.kuauthorAltuntaş, Muzaffer Ozan
dc.contributor.kuprofileTeaching Faculty
dc.contributor.schoolcollegeinstituteSchool of Medicine
dc.contributor.yokid169795
dc.date.accessioned2024-11-10T00:04:58Z
dc.date.issued2021
dc.description.abstractPurpose: Our study aimed to quantify the impact of submandibular gland (SMG) resection during Level I neck dissection (ND) on stimulated salivary output (SSO) and xerostomia-related quality of life in patients with head and neck cancer (HNC). Methods: A retrospective cohort was formed from 32 patients that underwent unilateral or bilateral Level I ND and a control group of 23 patients that had level II-IV ND. SSO (Saxon test) and University of Washington Quality of Life survey results for both groups were compared. Results: Mean SSO was 3.41 g in the SMG resection group and 3.86 g in the control group, with no significant statistical difference. There was no difference in mean SSO between patients with 2 SMGs, a single remaining SMG, or no glands. The mean SSO of SMG resection cases with a history of adjuvant RT was 2.61 g which was below the xerostomia threshold for the Saxon test (2.75 g) and control group patients with RT had a significantly higher mean SSO (4.07 g). The lowest UW-QoL saliva domain score average (53.8) was in the SMG-resected, RT-positive group. Conclusion: Results indicate unilateral or bilateral resection of SMG does not reduce SSO to a significant extent. Adjuvant radiotherapy and SMG resection are additive risk factors for xerostomia and the related loss in quality of life. SMG sparing may be necessary in HNC patients with higher risk for the need of adjuvant radiation.
dc.description.indexedbyWoS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.issue5
dc.description.openaccessNO
dc.description.volume83
dc.identifier.doi10.1159/000514134
dc.identifier.eissn1423-0275
dc.identifier.issn0301-1569
dc.identifier.scopus2-s2.0-85103430556
dc.identifier.urihttp://dx.doi.org/10.1159/000514134
dc.identifier.urihttps://hdl.handle.net/20.500.14288/16364
dc.identifier.wos632538500001
dc.keywordsNeck dissection
dc.keywordsSubmandibular gland
dc.keywordsXerostomia
dc.keywordsQuality of life
dc.languageEnglish
dc.publisherKarger
dc.sourceOrl-Journal For Oto-Rhino-Laryngology Head and Neck Surgery
dc.subjectOtorhinolaryngology
dc.titleDoes submandibular gland sacrificing neck dissection decrease salivary output and quality of life?
dc.typeJournal Article
dspace.entity.typePublication
local.contributor.authorid0000-0002-8747-7420
local.contributor.kuauthorAltuntaş, Muzaffer Ozan

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