Publication:
Gut microbiota and inflammation in chronic kidney disease and their roles in the development of cardiovascular disease

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dc.contributor.coauthorAfşar, Barış
dc.contributor.coauthorCovic, Adrian
dc.contributor.coauthorVaziri, Nosratola D.
dc.contributor.departmentN/A
dc.contributor.kuauthorÖnal, Emine Meltem
dc.contributor.kuauthorKanbay, Mehmet
dc.contributor.kuprofileFaculty Member
dc.contributor.schoolcollegeinstituteSchool of Medicine
dc.contributor.yokidN/A
dc.contributor.yokid110580
dc.date.accessioned2024-11-09T11:52:28Z
dc.date.issued2019
dc.description.abstractThe health and proper functioning of the cardiovascular and renal systems largely depend on crosstalk in the gut-kidney-heart/vessel triangle. Recent evidence suggests that the gut microbiota has an integral function in this crosstalk. Mounting evidence indicates that the development of chronic kidney and cardiovascular diseases follows chronic inflammatory processes that are affected by the gut microbiota via various immune, metabolic, endocrine, and neurologic pathways. Additionally, deterioration of the function of the cardiovascular and renal systems has been reported to disrupt the original gut microbiota composition, further contributing to the advancement of chronic cardiovascular and renal diseases. Considering the interaction between the gut microbiota and the renal and cardiovascular systems, we can infer that interventions for the gut microbiota through diet and possibly some medications can prevent/stop the vicious cycle between the gut microbiota and the cardiovascular/renal systems, leading to a decrease in chronic cardiovascular and renal diseases.
dc.description.fulltextYES
dc.description.indexedbyWoS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.issue2
dc.description.openaccessYES
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuN/A
dc.description.sponsorshipN/A
dc.description.versionPublisher version
dc.description.volume42
dc.formatpdf
dc.identifier.doi10.1038/s41440-018-0144-z
dc.identifier.embargoNO
dc.identifier.filenameinventorynoIR01720
dc.identifier.issn0916-9636
dc.identifier.linkhttps://doi.org/10.1038/s41440-018-0144-z
dc.identifier.quartileQ2
dc.identifier.scopus2-s2.0-85057590896
dc.identifier.urihttps://hdl.handle.net/20.500.14288/742
dc.identifier.wos457729000001
dc.keywordsGut microbiota
dc.keywordsChronic kidney disease
dc.keywordsUremic toxins
dc.keywordsCardiovascular disease
dc.languageEnglish
dc.publisherNature Publishing Group (NPG)
dc.relation.grantnoNA
dc.relation.urihttp://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/8295
dc.sourceHypertension Research
dc.subjectMedicine
dc.subjectCardiovascular system and cardiology
dc.titleGut microbiota and inflammation in chronic kidney disease and their roles in the development of cardiovascular disease
dc.typeReview
dspace.entity.typePublication
local.contributor.authoridN/A
local.contributor.authorid0000-0002-1297-0675
local.contributor.kuauthorÖnal, Emine Meltem
local.contributor.kuauthorKanbay, Mehmet

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