Publication: Derivation of neural stem cells from mouse induced pluripotent stem cells
Program
KU-Authors
KU Authors
Co-Authors
N/A
Advisor
Publication Date
2016
Language
English
Type
Book Chapter
Journal Title
Journal ISSN
Volume Title
Abstract
Neural stem cells (NSCs) derived from induced pluripotent stem cells offer therapeutic tools for neurodegenerative diseases. This review focuses on embryoid body (EB)-mediated stem cell culture techniques used to derive NSCs from mouse induced pluripotent stem cells (iPSCs). Generation of healthy and stable NSCs from iPSCs heavily depends on standardized in vitro cell culture systems that mimic the embryonic environments utilized during neural development. Specifically, the neural induction and expansion methods after EB formation are described in this review.
Description
Source:
Induced Pluripotent Stem (Ips) Cells: Methods And Protocols
Publisher:
Humana Press Inc
Keywords:
Subject
Biochemical research methods, Biochemistry, Molecular biology, Genetics, Heredity