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Publication:
Derivation of neural stem cells from mouse induced pluripotent stem cells

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SCHOOL OF MEDICINE
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Date

2016

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Book Chapter

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Abstract

Neural stem cells (NSCs) derived from induced pluripotent stem cells offer therapeutic tools for neurodegenerative diseases. This review focuses on embryoid body (EB)-mediated stem cell culture techniques used to derive NSCs from mouse induced pluripotent stem cells (iPSCs). Generation of healthy and stable NSCs from iPSCs heavily depends on standardized in vitro cell culture systems that mimic the embryonic environments utilized during neural development. Specifically, the neural induction and expansion methods after EB formation are described in this review.

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Humana Press

Subject

Biochemical research methods , Biochemistry , Molecular biology , Genetics , Heredity

Citation

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Source

Induced Pluripotent Stem (Ips) Cells: Methods And Protocols

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DOI

10.1007/7651_2015_227

URI

https://doi.org/10.1007/7651_2015_227
 https://hdl.handle.net/20.500.14288/14220

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Item type:Goal, Access status: Open Access ,
03 - Good Health and Well-being
Over the last 15 years, the number of childhood deaths has been cut in half. This proves that it is possible to win the fight against almost every disease. Still, we are spending an astonishing amount of money and resources on treating illnesses that are surprisingly easy to prevent. The new goal for worldwide Good Health promotes healthy lifestyles, preventive measures and modern, efficient healthcare for everyone.
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