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Derivation of neural stem cells from mouse induced pluripotent stem cells

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dc.contributor.coauthorN/A
dc.contributor.departmentSchool of Medicine
dc.contributor.kuauthorKaranfil, Işıl
dc.contributor.kuauthorÖnder, Tuğba Bağcı
dc.contributor.schoolcollegeinstituteSCHOOL OF MEDICINE
dc.date.accessioned2024-11-09T23:48:01Z
dc.date.issued2016
dc.description.abstractNeural stem cells (NSCs) derived from induced pluripotent stem cells offer therapeutic tools for neurodegenerative diseases. This review focuses on embryoid body (EB)-mediated stem cell culture techniques used to derive NSCs from mouse induced pluripotent stem cells (iPSCs). Generation of healthy and stable NSCs from iPSCs heavily depends on standardized in vitro cell culture systems that mimic the embryonic environments utilized during neural development. Specifically, the neural induction and expansion methods after EB formation are described in this review.
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.openaccessNO
dc.description.sponsoredbyTubitakEuN/A
dc.description.sponsorshipFP7 Marie Curie CIG
dc.description.sponsorshipKoc University School of Medicine This work is supported by FP7 Marie Curie CIG and Koc University School of Medicine.
dc.description.volume1357
dc.identifier.doi10.1007/7651_2015_227
dc.identifier.eissn1940-6029
dc.identifier.isbn978-1-4939-3055-5
dc.identifier.isbn978-1-4939-3054-8
dc.identifier.issn1064-3745
dc.identifier.urihttps://doi.org/10.1007/7651_2015_227
dc.identifier.urihttps://hdl.handle.net/20.500.14288/14220
dc.identifier.wos696318400022
dc.keywordsInduced pluripotent stem cells
dc.keywordsNeural stem cells
dc.keywordsEmbryoid body
dc.keywordsStem cell protocols
dc.keywordsNeural induction
dc.keywordsFibroblasts
dc.keywordsInduction
dc.keywordsSystems
dc.keywordsNeurons
dc.language.isoeng
dc.publisherHumana Press Inc
dc.relation.ispartofInduced Pluripotent Stem (Ips) Cells: Methods And Protocols
dc.subjectBiochemical research methods
dc.subjectBiochemistry
dc.subjectMolecular biology
dc.subjectGenetics
dc.subjectHeredity
dc.titleDerivation of neural stem cells from mouse induced pluripotent stem cells
dc.typeBook Chapter
dspace.entity.typePublication
local.contributor.kuauthorKaranfil, Işıl
local.contributor.kuauthorÖnder, Tuğba Bağcı
local.publication.orgunit1SCHOOL OF MEDICINE
local.publication.orgunit2School of Medicine
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relation.isOrgUnitOfPublication.latestForDiscoveryd02929e1-2a70-44f0-ae17-7819f587bedd
relation.isParentOrgUnitOfPublication17f2dc8e-6e54-4fa8-b5e0-d6415123a93e
relation.isParentOrgUnitOfPublication.latestForDiscovery17f2dc8e-6e54-4fa8-b5e0-d6415123a93e

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