Publication:
The effect of chronic kidney disease on lipid metabolism

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dc.contributor.coauthorAfsar, Baris
dc.contributor.coauthorCovic, Adrian
dc.contributor.coauthorOrtiz, Alberto
dc.contributor.departmentN/A
dc.contributor.kuauthorKanbay, Mehmet
dc.contributor.kuauthorDinçer, Neris
dc.contributor.kuauthorDağel, Tuncay
dc.contributor.kuprofileFaculty Member
dc.contributor.kuprofileUndergraduate Student
dc.contributor.kuprofileDoctor
dc.contributor.schoolcollegeinstituteSchool of Medicine
dc.contributor.schoolcollegeinstituteSchool of Medicine
dc.contributor.schoolcollegeinstituteN/A
dc.contributor.unitN/A
dc.contributor.unitN/A
dc.contributor.unitKoç University Hospital
dc.contributor.yokid110580
dc.contributor.yokid349025
dc.contributor.yokidN/A
dc.date.accessioned2024-11-09T22:57:49Z
dc.date.issued2019
dc.description.abstractThe major cause of death among chronic kidney disease patients is cardiovascular diseases. Cardiovascular and kidney disease are interrelated and increase the severity of each other. Dyslipidemia is one the major causes of cardiovascular disease among chronic kidney disease patients along with diabetes and hypertension. The relationship between dyslipidemia and chronic kidney disease is reciprocal. Dyslipidemia is known to be a risk factor for chronic kidney disease and chronic kidney disease causes major alterations on lipoprotein profile, defined as the dyslipidemic profile of chronic kidney disease patients. Increased triglyceride, very low density lipoprotein and oxidized low density lipoprotein as well as decreased high density lipoprotein and changes in the composition of lipoproteins contribute to the dyslipidemic profile. Treatment strategies targeting the dyslipidemic profile of chronic kidney disease could contribute to prevent cardiovascular diseases. Current therapy is based on the patient kidney function and consist mainly of statins. This review focuses on the effects of chronic kidney disease on the lipoprotein profile and how this may impact novel therapeutic approaches to cardiovascular risk.
dc.description.indexedbyWoS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.issue2
dc.description.openaccessNO
dc.description.publisherscopeInternational
dc.description.sponsorshipRepublic of Turkey Ministry of Development
dc.description.sponsorshipFIS [PI16/02057]
dc.description.sponsorshipISCIII-RETIC REDinREN FEDER funds [RD016/0009]
dc.description.sponsorshipSociedad Espanola de Nefrologia
dc.description.sponsorshipFundacion Renal Inigo Alvarez de Toledo (FRIAT)
dc.description.sponsorshipComunidad de Madrid Biomedicina [B2017/BMD-3686 CIFRA2-CM] MK gratefully acknowledges use of the services and facilities of the KoC University Research Center for Translational Medicine (KUTTAM), funded by the Republic of Turkey Ministry of Development. The content is solely the responsibility of the authors and does not necessarily represent the official views of the Ministry of Development. AO was supported by FIS PI16/02057, ISCIII-RETIC REDinREN RD016/0009 FEDER funds, Sociedad Espanola de Nefrologia, Fundacion Renal Inigo Alvarez de Toledo (FRIAT), Comunidad de Madrid Biomedicina B2017/BMD-3686 CIFRA2-CM.
dc.description.volume51
dc.identifier.doi10.1007/s11255-018-2047-y
dc.identifier.eissn1573-2584
dc.identifier.issn0301-1623
dc.identifier.quartileQ3
dc.identifier.scopus2-s2.0-85058014861
dc.identifier.urihttp://dx.doi.org/10.1007/s11255-018-2047-y
dc.identifier.urihttps://hdl.handle.net/20.500.14288/7615
dc.identifier.wos459537700013
dc.keywordsChronic kidney disease
dc.keywordsPCSK9
dc.keywordsCholesterol
dc.keywordsTriglycerides
dc.keywordsHDL
dc.keywordsLDL
dc.keywordsHigh-density-lipoprotein
dc.keywordsCoronary-artery-disease
dc.keywordsExtended-release niacin
dc.keywordsStage renal-disease
dc.keywordsCardiovascular events
dc.keywordsldl cholesterol
dc.keywordsOxidized ldl
dc.keywordsEndothelial dysfunction
dc.keywordsManaging dyslipidemia
dc.keywordsHemodialysis-patients
dc.languageEnglish
dc.publisherSpringer
dc.sourceInternational Urology and Nephrology
dc.subjectUrology
dc.subjectNephrology
dc.titleThe effect of chronic kidney disease on lipid metabolism
dc.typeReview
dspace.entity.typePublication
local.contributor.authorid0000-0002-1297-0675
local.contributor.authorid0000-0003-1746-4736
local.contributor.authorid0000-0002-1281-6571
local.contributor.kuauthorKanbay, Mehmet
local.contributor.kuauthorDinçer, Neris
local.contributor.kuauthorDağel, Tuncay

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