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The effect of chronic kidney disease on lipid metabolism

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dc.contributor.coauthorAfsar, Baris
dc.contributor.coauthorCovic, Adrian
dc.contributor.coauthorOrtiz, Alberto
dc.contributor.departmentSchool of Medicine
dc.contributor.facultymemberYes
dc.contributor.kuauthorDağel, Tuncay
dc.contributor.kuauthorDinçer, Neris
dc.contributor.kuauthorKanbay, Mehmet
dc.contributor.schoolcollegeinstituteSCHOOL OF MEDICINE
dc.date.accessioned2024-11-09T22:57:49Z
dc.date.issued2019
dc.description.abstractThe major cause of death among chronic kidney disease patients is cardiovascular diseases. Cardiovascular and kidney disease are interrelated and increase the severity of each other. Dyslipidemia is one the major causes of cardiovascular disease among chronic kidney disease patients along with diabetes and hypertension. The relationship between dyslipidemia and chronic kidney disease is reciprocal. Dyslipidemia is known to be a risk factor for chronic kidney disease and chronic kidney disease causes major alterations on lipoprotein profile, defined as the dyslipidemic profile of chronic kidney disease patients. Increased triglyceride, very low density lipoprotein and oxidized low density lipoprotein as well as decreased high density lipoprotein and changes in the composition of lipoproteins contribute to the dyslipidemic profile. Treatment strategies targeting the dyslipidemic profile of chronic kidney disease could contribute to prevent cardiovascular diseases. Current therapy is based on the patient kidney function and consist mainly of statins. This review focuses on the effects of chronic kidney disease on the lipoprotein profile and how this may impact novel therapeutic approaches to cardiovascular risk.
dc.description.fulltextNo
dc.description.harvestedfromManual
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.openaccessNO
dc.description.peerreviewstatusN/A
dc.description.publisherscopeInternational
dc.description.readpublishN/A
dc.description.sponsoredbyTubitakEuN/A
dc.description.studentonlypublicationNo
dc.description.studentpublicationYes
dc.description.versionN/A
dc.identifier.WoSQuartileQ2
dc.identifier.doi10.1007/s11255-018-2047-y
dc.identifier.eissn1573-2584
dc.identifier.embargoN/A
dc.identifier.endpage277
dc.identifier.issn0301-1623
dc.identifier.issue2
dc.identifier.pubmed30519980
dc.identifier.scopus2-s2.0-85058014861
dc.identifier.startpage265
dc.identifier.urihttps://doi.org/10.1007/s11255-018-2047-y
dc.identifier.urihttps://hdl.handle.net/20.500.14288/7615
dc.identifier.volume51
dc.identifier.wos000459537700013
dc.keywordsChronic kidney disease
dc.keywordsPCSK9
dc.keywordsCholesterol
dc.keywordsTriglycerides
dc.keywordsHDL
dc.keywordsLDL
dc.language.isoeng
dc.publisherSpringer
dc.relation.affiliationKoç University
dc.relation.collectionKoç University Institutional Repository
dc.relation.ispartofInternational Urology and Nephrology
dc.relation.openaccessN/A
dc.rightsN/A
dc.subjectUrology
dc.subjectNephrology
dc.titleThe effect of chronic kidney disease on lipid metabolism
dc.typeReview
dspace.entity.typePublication
local.contributor.kuauthorKanbay, Mehmet
local.contributor.kuauthorDinçer, Neris
local.contributor.kuauthorDağel, Tuncay
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relation.isGoalOfPublication.latestForDiscoverya9786601-9431-4553-9a46-013bb366fb87
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