Publication: Trans-arterial radioembolization with Yttrium-90 of unresectable and systemic chemotherapy resistant hepatoblastoma in three toddlers
Program
KU-Authors
KU Authors
Co-Authors
Balli, Hüseyin Tuğsan
Aikimbaev, Kairgeldy
Güney, İsa Burak
Pişkin, Ferhat Can
Yağcı-Küpeli, Begül
Küpeli, Serhan
Advisor
Publication Date
Language
English
Type
Journal Title
Journal ISSN
Volume Title
Abstract
The aim of this short communication was to report the results of transarterial radioembolization (TARE) with Yttrium-90 (Y90) loaded resin microspheres in three toddlers with unresectable and systemic chemotherapy-resistant HB hepatoblastoma (HB). Six TARE procedures were performed on the patients. The dose required for treatment was calculated using partition model. Administered doses of Y90 were 1.369, 0.851, and 1.147 GBq. Complete radiological response in two patients and partial response enabling liver resection in one patient were achieved. Neither life-threatening nor minor complications developed after the treatment. These results demonstrates that HB is a radiosensitive neoplasm, and TARE-Y90 can be used as the primary, neoadjuvant and palliative treatment method in patients with unresectable and systemic chemotherapy-resistant HBs. However, studies with higher number of patients and long-term results are required.
Description
Source:
Cardiovascular and Interventional Radiology
Publisher:
Springer
Keywords:
Subject
Cardiac and cardiovascular systems, Radiology, Nuclear medicine, Medical imaging