Publication:
Thiophene-based trimers for in vivo electronic functionalization of tissues

dc.contributor.coauthorMantione, Daniele
dc.contributor.coauthorDufil, Gwennael
dc.contributor.coauthorVallan, Lorenzo
dc.contributor.coauthorParker, Daniela
dc.contributor.coauthorBrochon, Cyril
dc.contributor.coauthorCloutet, Eric
dc.contributor.coauthorHadziioannou, Georges
dc.contributor.coauthorBerggren, Magnus
dc.contributor.coauthorStavrinidou, Eleni
dc.contributor.coauthorPavlopoulou, Eleni
dc.contributor.departmentDepartment of Mechanical Engineering
dc.contributor.kuauthorİstif, Emin
dc.contributor.schoolcollegeinstituteCollege of Engineering
dc.date.accessioned2024-11-09T13:51:30Z
dc.date.issued2020
dc.description.abstractElectronic materials that can self-organize in vivo and form functional components along the tissue of interest can result in a seamless integration of the bioelectronic interface. Previously, we presented in vivo polymerization of the conjugated oligomer ETE-S in plants, forming conductors along the plant structure. The EDOT-thiophene-EDOT trimer with a sulfonate side group polymerized due to the native enzymatic activity of the plant and integrated within the plant cell wall. Here, we present the synthesis of three different conjugated trimers based on thiophene and EDOT or purely EDOT trimers that are able to polymerize enzymatically in physiological pH in vitro as well as in vivo along the roots of living plants. We show that by modulating the backbone and the side chain, we can tune the electronic properties of the resulting polymers as well as their localization and penetration within the root. Our work paves the way for the rational design of electronic materials that can self-organize in vivo for spatially controlled electronic functionalization of living tissue.
dc.description.fulltextYES
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.issue12
dc.description.openaccessYES
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuEU
dc.description.sponsorshipEuropean Union (EU)
dc.description.sponsorshipHorizon 2020
dc.description.sponsorshipResearch and Innovation Program
dc.description.sponsorshipHyPhOE
dc.description.sponsorshipMSCA-IF-2018
dc.description.sponsorshipTEXTHIOL
dc.description.versionPublisher version
dc.description.volume2
dc.identifier.doi10.1021/acsaelm.0c00861
dc.identifier.eissn2637-6113
dc.identifier.embargoNO
dc.identifier.filenameinventorynoIR02601
dc.identifier.quartileQ2
dc.identifier.scopus2-s2.0-85097874496
dc.identifier.urihttps://hdl.handle.net/20.500.14288/3950
dc.identifier.wos603295000032
dc.keywordsBioelectronics
dc.keywordsConducting polymers
dc.keywordsEDOT
dc.keywordsEnzymatic polymerization
dc.keywordsPlant-mediated polymerization
dc.keywordsTissue engineering
dc.language.isoeng
dc.publisherAmerican Chemical Society (ACS)
dc.relation.grantno800926
dc.relation.grantno838171
dc.relation.ispartofACS Applied Electronic Materials
dc.relation.urihttp://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/9240
dc.subjectEngineering
dc.subjectMaterials science
dc.titleThiophene-based trimers for in vivo electronic functionalization of tissues
dc.typeJournal Article
dspace.entity.typePublication
local.contributor.kuauthorİstif, Emin
local.publication.orgunit1College of Engineering
local.publication.orgunit2Department of Mechanical Engineering
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