Publication: AI-assisted optoelectrokinetic control of active self-propelling micromotors for independent navigation with multimode motions
| dc.contributor.coauthor | Liu, J. | |
| dc.contributor.coauthor | Zheng, Z. | |
| dc.contributor.coauthor | Hou, Y. | |
| dc.contributor.coauthor | Shi, Q. | |
| dc.contributor.coauthor | Huang, Q. | |
| dc.contributor.coauthor | Han, J. | |
| dc.contributor.coauthor | Wang, H. | |
| dc.contributor.department | School of Medicine | |
| dc.contributor.department | Department of Mechanical Engineering | |
| dc.contributor.kuauthor | Sitti, Metin | |
| dc.contributor.schoolcollegeinstitute | SCHOOL OF MEDICINE | |
| dc.contributor.schoolcollegeinstitute | College of Engineering | |
| dc.date.accessioned | 2026-09-15T10:56:24Z | |
| dc.date.issued | 2026 | |
| dc.description.abstract | Agile and controllable motion is essential for active micromotors to navigate various microscale scenarios and manipulate the microscopic world, where parallel navigation and independent control are highly desirable. However, most micromotor navigation strategies suffer from limited agility and poor predictability, with motion typically confined to single-micromotor self-propulsion along predetermined trajectories. Herein, we propose an artificial intelligence (AI)–assisted optoelectronic control strategy that involves converting stochastic micromotor self-propulsion into controllable omnidirectional motion by synergistically exploiting multiple electrokinetic mechanisms. This strategy enables independent navigation of individual micromotors while simultaneously supporting parallel manipulation. By spatiotemporally configuring two or more optical patterns, agile motion primitives, such as directional propulsion, passive propulsion, in situ U-turns, and motion pause and restarting, were developed. To improve navigation robustness under coupled electrokinetic effects, a spatial-temporal AI model was developed for accurately predicting micromotor motion to facilitate the optimization of dynamic guidance schemes. These motion primitives are sequentially integrated and automatedly switched along long-term, reconfigurable trajectories, thereby enabling continuous navigation guided by discrete optical patterns. Independent control of active micromotors was demonstrated through the parallel manipulation of multiple Janus micromotors that were navigating intricate networks, in which each micromotor followed individual trajectories and adapted in real time to local terrain variations. This work showcased an agile and predictable navigation strategy for active micromotors that facilitates independent and massively parallel manipulation in intricate terrains, thus opening further possibilities for advanced applications. | |
| dc.description.harvestedfrom | Manual | |
| dc.description.indexedby | WOS | |
| dc.description.indexedby | Scopus | |
| dc.description.indexedby | PubMed | |
| dc.description.publisherscope | International | |
| dc.description.sponsoredbyTubitakEu | N/A | |
| dc.description.sponsorship | National Natural Science Foundation of China (Grant: 62403056); National Natural Science Foundation of China (Grant: 62573060); Fundamental Research Funds for the Central Universities (Grant: 2025CX01003); National Key Research and Development Program of China (Grant: 2023YFB4705400); Beijing Natural Science Foundation (Grant: L242023) [Funding]: This work was supported by the National Natural Science Foundation of China under grant number 62573060 (H.W.), National Natural Science Foundation of China under grant number 62403056 (Y.H.), Beijing Natural Science Foundation under grant L242023 (H.W.), and Fundamental Research Funds for the Central Universities under grant 2025CX01003 (H.W.). [Acknowledgements]: We thank C. Li and Z. Li for assistance in active micromotor fabrication. Funding: This work was supported by the National Natural Science Foundation of China under grant number 62573060 (H.W.), National Natural Science Foundation of China under grant number 62403056 (Y.H.), Beijing Natural Science Foundation under grant L242023 (H.W.), and Fundamental Research Funds for the Central Universities under grant 2025CX01003 (H.W.). Author contributions: Conceptualization: J.L. and Z.Z. Methodology: J.L. and Z.Z. Investigation: J.L., Z.Z., Q.S., and Q.H. Funding acquisition: H.W. and M.S. Supervision: H.W., M.S., Q.S., and Q.H. Writing—original draft: J.L., Z.Z., J.H., H.W., and M.S. Writing—review and editing: Y.H., H.W., and M.S. Competing interests: The authors declare that they have no competing interests. Data, code, and materials availability: All data needed to evaluate and reproduce the results in the paper are present in the paper and/or the Supplementary Materials. The source code is fully available at https://github.com/husandaimei/ResNet-Transformer-for-motion-prediction.git and https://doi.org/10.5281/zenodo.19245390 . This study did not generate new materials. | |
| dc.description.version | Published Version | |
| dc.identifier.ScopusPercentile | 96 | |
| dc.identifier.ScopusQuartile | Q1 | |
| dc.identifier.WoSPercentile | 91.8 | |
| dc.identifier.WoSQuartile | Q1 | |
| dc.identifier.doi | 10.1126/sciadv.aef0741 | |
| dc.identifier.eissn | 2375-2548 | |
| dc.identifier.endpage | - | |
| dc.identifier.grantno | 62403056 | |
| dc.identifier.grantno | 62573060 | |
| dc.identifier.grantno | 2025CX01003 | |
| dc.identifier.grantno | 2023YFB4705400 | |
| dc.identifier.grantno | L242023 | |
| dc.identifier.issn | 2375-2548 | |
| dc.identifier.issue | 33 | |
| dc.identifier.pubmed | 42600016 | |
| dc.identifier.scopus | 2-s2.0-105047563716 | |
| dc.identifier.startpage | - | |
| dc.identifier.uri | http://doi.org/10.1126/sciadv.aef0741 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.14288/35499 | |
| dc.identifier.volume | 12 | |
| dc.keywords | Microscale chemistry | |
| dc.keywords | Motion control | |
| dc.keywords | Motion planning | |
| dc.keywords | Robustness (evolution) | |
| dc.keywords | Roaming | |
| dc.keywords | Motion (physics) | |
| dc.keywords | Electrokinetic phenomena | |
| dc.keywords | Trajectory | |
| dc.language | eng | |
| dc.publisher | American Association for the Advancement of Science (AAAS) | |
| dc.relation.affiliation | Koç University | |
| dc.relation.collection | Koç University Institutional Repository | |
| dc.relation.ispartof | Science Advances | |
| dc.relation.openaccess | N/A | |
| dc.subject | Physical sciences | |
| dc.subject | Physics and astronomy | |
| dc.subject | Condensed matter physics | |
| dc.subject | Engineering | |
| dc.subject | Biomedical engineering | |
| dc.subject | Mechanical engineering | |
| dc.title | AI-assisted optoelectrokinetic control of active self-propelling micromotors for independent navigation with multimode motions | |
| dc.type | Journal Article | |
| dspace.entity.type | Publication | |
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