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Bone pain ıs associated with short radiographic progression-free survival in patients with metastatic castration-sensitive prostate cancer

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dc.contributor.coauthorÖzmen, A.
dc.contributor.coauthorKapar, C.
dc.contributor.coauthorGültürk, İ.
dc.contributor.coauthorŞahin, S.
dc.contributor.coauthorŞeker, K. G.
dc.contributor.coauthorTuğcu, V.
dc.contributor.departmentKUH (Koç University Hospital)
dc.contributor.kuauthorTural, Deniz
dc.contributor.schoolcollegeinstituteKUH (KOÇ UNIVERSITY HOSPITAL)
dc.date.accessioned2026-07-17T08:28:37Z
dc.date.issued2026
dc.description.abstractWe aimed to evaluate the prognostic significance of bone pain at presentation in metastatic castration-sensitive prostate cancer (mCSPC) and its association with radiographic progression-free survival (rPFS), independent of established prognostic factors. Methods: We retrospectively analyzed 205 patients with mCSPC treated at our center. Data were obtained from patient files and hospital records. rPFS was estimated using the Kaplan–Meier method and compared using the log-rank test. Baseline characteristics according to bone pain status were compared using the χ2 test for categorical variables and the Wilcoxon test for continuous variables. Results: Median rPFS for the entire cohort was 23.8 months (95% CI: 18.6–29.0). In univariate analysis, median rPFS was significantly shorter in patients with bone pain compared to those without (16.9 vs. 29.5 months, p
dc.description.harvestedfromManual
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.publisherscopeInternational
dc.description.readpublishN/A
dc.description.sponsoredbyTubitakEuN/A
dc.description.versionPublished Version
dc.identifier.WoSQuartileQ1
dc.identifier.doi10.3390/jcm15103968
dc.identifier.eissn2077-0383
dc.identifier.embargoN/A
dc.identifier.issue10
dc.identifier.pubmed42194929
dc.identifier.scopus2-s2.0-105039995371
dc.identifier.urihttp://doi.org/10.3390/jcm15103968
dc.identifier.urihttps://hdl.handle.net/20.500.14288/33399
dc.identifier.volume15
dc.identifier.wos001776458800001
dc.keywordsBone pain
dc.keywordsPrognostic factors
dc.keywordsProstate cancer
dc.keywordsRadiographic progression-free survival
dc.languageeng
dc.publisherMDPI
dc.relation.affiliationKoç University
dc.relation.collectionKoç University Institutional Repository
dc.relation.ispartofJournal of Clinical Medicine
dc.relation.openaccessN/A
dc.rightsN/A
dc.rights.uriN/A
dc.subjectInternal medicine
dc.titleBone pain ıs associated with short radiographic progression-free survival in patients with metastatic castration-sensitive prostate cancer
dc.typeJournal Article
dspace.entity.typePublication
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