Publication: Bone pain ıs associated with short radiographic progression-free survival in patients with metastatic castration-sensitive prostate cancer
Program
KU-Authors
KU Authors
Co-Authors
Özmen, A.
Kapar, C.
Gültürk, İ.
Şahin, S.
Şeker, K. G.
Tuğcu, V.
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Date
Language
eng
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N/A
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Abstract
We aimed to evaluate the prognostic significance of bone pain at presentation in metastatic castration-sensitive prostate cancer (mCSPC) and its association with radiographic progression-free survival (rPFS), independent of established prognostic factors. Methods: We retrospectively analyzed 205 patients with mCSPC treated at our center. Data were obtained from patient files and hospital records. rPFS was estimated using the Kaplan–Meier method and compared using the log-rank test. Baseline characteristics according to bone pain status were compared using the χ2 test for categorical variables and the Wilcoxon test for continuous variables. Results: Median rPFS for the entire cohort was 23.8 months (95% CI: 18.6–29.0). In univariate analysis, median rPFS was significantly shorter in patients with bone pain compared to those without (16.9 vs. 29.5 months, p
Source
Publisher
MDPI
Subject
Internal medicine
Citation
Has Part
Source
Journal of Clinical Medicine
Book Series Title
Edition
DOI
10.3390/jcm15103968
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