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An integrated and flexible ultrasonic device for continuous bladder volume monitoring

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dc.contributor.coauthorAkcoren, Dincay
dc.contributor.coauthorEminoglu, Burak
dc.contributor.departmentDepartment of Mechanical Engineering
dc.contributor.departmentGraduate School of Sciences and Engineering
dc.contributor.departmentSchool of Medicine
dc.contributor.kuauthorAli, Mohsin
dc.contributor.kuauthorBardakçı, Emine
dc.contributor.kuauthorBeker, Levent
dc.contributor.kuauthorKılıç, Rasim
dc.contributor.kuauthorKöseoğlu, Ersin
dc.contributor.kuauthorTarcan, Tufan
dc.contributor.kuauthorTemel, Özgür Deniz
dc.contributor.kuauthorToymus, Alp Timuçin
dc.contributor.kuauthorYener, Umut Can
dc.contributor.schoolcollegeinstituteCollege of Engineering
dc.contributor.schoolcollegeinstituteGRADUATE SCHOOL OF SCIENCES AND ENGINEERING
dc.contributor.schoolcollegeinstituteSCHOOL OF MEDICINE
dc.date.accessioned2024-12-29T09:39:01Z
dc.date.issued2024
dc.description.abstractBladder volume measurement is critical for early detection and management of lower urinary tract dysfunctions. Current gold standard is invasive, and alternative technologies either require trained personnel or do not offer medical grade information. Here, we report an integrated wearable ultrasonic bladder volume monitoring device for accurate and autonomous continuous monitoring of the bladder volume. The device incorporates flexible and air-backed ultrasonic transducers and miniaturized control electronics with wireless data transmission capability. We demonstrate the real-life application of the device on healthy volunteers with various bladder shapes and sizes with high accuracy. Apart from the lower urinary tract dysfunctions, the proposed technology could also be adapted for various wearable ultrasonic applications. © The Author(s) 2024.
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.issue1
dc.description.openaccessAll Open Access
dc.description.openaccessGold Open Access
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuTÜBİTAK
dc.description.sponsorshipFunding text 1: We thank Gokberk Toymus for discussions on lower urinary tract dysfunctions, Seckin Akinci and Fariborz Mirlou for the help with PCB design and fabrication, Mohammad Meraj Ghanbari for the help with the pulser, Prof. Dr. Hayrettin Koymen for discussions on ultrasonic transducers, Ecem Ezgi Ozkahraman for the help with in-vivo measurements and the feedback on the manuscript. A.T.T is supported by the Scientific and Technological Research Council of Turkey (TUBITAK) through the 2232 (grant no. 118C295) program. U.C.Y. is supported by TUBITAK through the 2210/A program. E.B. is supported by TUBITAK through the 2210/C program. L.B. acknowledges the European Research Council (2ND-CHANCE,\u00A0grant no. 101043119). We acknowledge Ko\u00E7 University Surface Science and Technology Center (KUYTAM) and Ko\u00E7 University Nanofabrication and Nanocharacterization Center (n2STAR) for access to the infrastructure. The opinions expressed in this publication are those of the authors. They do not purport to reflect the opinions or views of the ADI, its subsidiaries, or employees.; Funding text 2: We thank Gokberk Toymus for discussions on lower urinary tract dysfunctions, Seckin Akinci and Fariborz Mirlou for the help with PCB design and fabrication, Mohammad Meraj Ghanbari for the help with the pulser, Prof. Dr. Hayrettin Koymen for discussions on ultrasonic transducers, Ecem Ezgi Ozkahraman for the help with in-vivo measurements and the feedback on the manuscript. A.T.T is supported by the Scientific and Technological Research Council of Turkey (TUBITAK) through the 2232 (grant no. 118C295) program. U.C.Y. is supported by TUBITAK through the 2210/A program. E.B. is supported by TUBITAK through the 2210/C program. L.B. acknowledges the European Research Council (2ND-CHANCE, grant no. 101043119). We acknowledge Ko\u00E7 University Surface Science and Technology Center (KUYTAM) and Ko\u00E7 University Nanofabrication and Nanocharacterization Center (n2STAR) for access to the infrastructure. The opinions expressed in this publication are those of the authors. They do not purport to reflect the opinions or views of the ADI, its subsidiaries, or employees.
dc.description.volume15
dc.identifier.doi10.1038/s41467-024-50397-8
dc.identifier.eissn2041-1723
dc.identifier.issn2041-1723
dc.identifier.link 
dc.identifier.quartileQ1
dc.identifier.scopus2-s2.0-85201719026
dc.identifier.urihttps://doi.org/10.1038/s41467-024-50397-8
dc.identifier.urihttps://hdl.handle.net/20.500.14288/22886
dc.keywordsAdult
dc.keywordsEquipment design
dc.keywordsFemale
dc.keywordsHealthy volunteers
dc.keywordsHumans
dc.keywordsMale
dc.keywordsMonitoring, physiologic
dc.keywordsOrgan size
dc.keywordsTransducers
dc.keywordsUltrasonography
dc.keywordsUrinary bladder
dc.keywordsWearable electronic devices
dc.keywordsWireless technology
dc.language.isoeng
dc.publisherNature Research
dc.relation.grantno 
dc.relation.ispartofNature Communications
dc.rights 
dc.subjectUrinary retention
dc.subjectEchography
dc.subjectBladder
dc.titleAn integrated and flexible ultrasonic device for continuous bladder volume monitoring
dc.typeJournal Article
dc.type.other 
dspace.entity.typePublication
local.contributor.kuauthorToymus, Alp Timuçin
local.contributor.kuauthorYener, Umut Can
local.contributor.kuauthorBardakçı, Emine
local.contributor.kuauthorTemel, Özgür Deniz
local.contributor.kuauthorKöseoğlu, Ersin
local.contributor.kuauthorAli, Mohsin
local.contributor.kuauthorKılıç, Rasim
local.contributor.kuauthorBeker, Levent
local.contributor.kuauthorTarcan, Tufan
local.publication.orgunit1GRADUATE SCHOOL OF SCIENCES AND ENGINEERING
local.publication.orgunit1SCHOOL OF MEDICINE
local.publication.orgunit1College of Engineering
local.publication.orgunit2Department of Mechanical Engineering
local.publication.orgunit2School of Medicine
local.publication.orgunit2Graduate School of Sciences and Engineering
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