Publication: Graft versus host disease after liver transplantation: a case report
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KU-Authors
KU Authors
Co-Authors
Acar, Sencan
Arat, Mutlu
Tecimer, Tulay
Polat, Kamil Yalcin
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Abstract
Graft Versus Host Disease (GVHD) is a severe immunological-clincopathological condition mediated by healthy T-lymphocytes in donor tissue against the immunosuppressed host tissue and rarely seen after solid organ transplantation (SOT). A 72-year old male patient underwent cadaveric liver transplantation. On day 34 of the postoperative follow-up, the patient developed fever, generalized skin rash and hemorrhagic lesions in the oropharynx. Skin biopsy was consistent with GVHD. Despite high-dose corticosteroid treatment, he died on postoperative day 51. Although it is seen rarely after liver transplantation, GVHD is an important clinical entity for which early diagnosis is critical due to its high rates of mortality.
Source
Publisher
Kare Yayıncılık
Subject
Gastroenterology and hepatology
Citation
Has Part
Source
Hepatology Forum
Book Series Title
Edition
DOI
10.14744/hf.2021.2021.9006