Publication: Fundus topographical distribution patterns of ocular toxoplasmosis
dc.contributor.coauthor | Halim, Muhammad Sohail | |
dc.contributor.coauthor | Özdal, Pınar Çakar | |
dc.contributor.coauthor | Ormaechea, Maria Soledad | |
dc.contributor.coauthor | Özdemir, Hüseyin Baran | |
dc.contributor.coauthor | Uludag, Gunay | |
dc.contributor.coauthor | Sredar, Nripun | |
dc.contributor.coauthor | Cankurtaran, Mahmut | |
dc.contributor.coauthor | Liu, Xiaoxuan | |
dc.contributor.coauthor | Denniston, Alastair Keith | |
dc.contributor.coauthor | Rudzinski, Marcelo N. | |
dc.contributor.coauthor | Colombero, Daniel N. | |
dc.contributor.coauthor | Schlaen, Bernardo Ariel | |
dc.contributor.coauthor | Keane, Pearse Andrew | |
dc.contributor.coauthor | Pavesio, Carlos | |
dc.contributor.coauthor | Nguyen, Quan Dong | |
dc.contributor.department | KUTTAM (Koç University Research Center for Translational Medicine) | |
dc.contributor.department | School of Medicine | |
dc.contributor.kuauthor | Hasanreisoğlu, Murat | |
dc.contributor.kuauthor | Kesim, Cem | |
dc.contributor.schoolcollegeinstitute | Research Center | |
dc.contributor.schoolcollegeinstitute | SCHOOL OF MEDICINE | |
dc.date.accessioned | 2024-11-09T23:09:34Z | |
dc.date.issued | 2023 | |
dc.description.abstract | Background: to establish topographic maps and determine fundus distribution patterns of ocular toxoplasmosis (OT) lesions. Methods: in this retrospective study, patients who presented with OT to ophthalmology clinics from four countries (Argentina, Turkey, UK, USA) were included. Size, shape and location of primary (1 degrees)/recurrent (2 degrees) and active/inactive lesions were converted into a two-dimensional retinal chart by a retinal drawing software. A final contour map of the merged image charts was then created using a custom Matlab programme. Descriptive analyses were performed. Results984 lesions in 514 eyes of 464 subjects (53% women) were included. Mean area of all 1 degrees and 2 degrees lesions was 5.96 +/- 12.26 and 5.21 +/- 12.77 mm(2), respectively. For the subset group lesions (eyes with both 1 degrees and 2 degrees lesions), 1 degrees lesions were significantly larger than 2 degrees lesions (5.52 +/- 6.04 mm(2) vs 4.09 +/- 8.90 mm(2), p=0.038). Mean distances from foveola to 1 degrees and 2 degrees lesion centres were 6336 +/- 4267 and 5763 +/- 3491 mu m, respectively. The majority of lesions were found in temporal quadrant (p<0.001). Maximum overlap of all lesions was at 278 mu m inferotemporal to foveola. Conclusion: the 1 degrees lesions were larger than 2 degrees lesions. The 2 degrees lesions were not significantly closer to fovea than 1 degrees lesions. Temporal quadrant and macular region were found to be densely affected underlining the vision threatening nature of the disease. | |
dc.description.indexedby | WOS | |
dc.description.indexedby | PubMed | |
dc.description.issue | - | |
dc.description.openaccess | NO | |
dc.description.publisherscope | International | |
dc.description.sponsoredbyTubitakEu | N/A | |
dc.description.volume | - | |
dc.identifier.doi | 10.1136/bjo-2022-322747 | |
dc.identifier.eissn | 1468-2079 | |
dc.identifier.issn | 0007-1161 | |
dc.identifier.quartile | Q1 | |
dc.identifier.scopus | 2-s2.0-85188760558 | |
dc.identifier.uri | https://doi.org/10.1136/bjo-2022-322747 | |
dc.identifier.uri | https://hdl.handle.net/20.500.14288/9327 | |
dc.identifier.wos | 957156300001 | |
dc.keywords | Retina | |
dc.keywords | Inflammation | |
dc.keywords | Infection | |
dc.keywords | Imaging | |
dc.keywords | Choroid | |
dc.language.iso | eng | |
dc.publisher | BMJ Publishing Group | |
dc.relation.ispartof | The British Journal of Ophthalmology | |
dc.subject | Ophthalmology | |
dc.title | Fundus topographical distribution patterns of ocular toxoplasmosis | |
dc.type | Journal Article | |
dspace.entity.type | Publication | |
local.contributor.kuauthor | Hasanreisoğlu, Murat | |
local.contributor.kuauthor | Kesim, Cem | |
local.publication.orgunit1 | SCHOOL OF MEDICINE | |
local.publication.orgunit1 | Research Center | |
local.publication.orgunit2 | KUTTAM (Koç University Research Center for Translational Medicine) | |
local.publication.orgunit2 | School of Medicine | |
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relation.isOrgUnitOfPublication | d02929e1-2a70-44f0-ae17-7819f587bedd | |
relation.isOrgUnitOfPublication.latestForDiscovery | 91bbe15d-017f-446b-b102-ce755523d939 | |
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