Publication:
Post-transplant IgA nephropathy: a rapidly evolving field of kidney transplant medicine

dc.contributor.coauthorBarratt, Jonathan
dc.contributor.departmentSchool of Medicine
dc.contributor.kuauthorÇöpür, Sidar
dc.contributor.kuauthorGüldan, Mustafa
dc.contributor.kuauthorKanbay, Mehmet
dc.contributor.kuauthorÖzbek, Laşin
dc.contributor.schoolcollegeinstituteSCHOOL OF MEDICINE
dc.date.accessioned2025-03-06T20:59:10Z
dc.date.issued2024
dc.description.abstractIgA nephropathy is the commonest pattern of primary glomerular disease in the world, with high rates of progression to kidney failure. As IgA nephropathy commonly causes kidney failure at a young age, kidney transplantation is commonly used to treat kidney failure. However, high rates of recurrent disease in the allograft remain a common management challenge. The prevalence of post-transplant recurrence approaches 15% at ten years post-transplant and is associated with poor allograft function and high rates of allograft loss. Post-transplant IgA nephropathy has also been described de novo in some case series. Treatment of recurrent IgA nephropathy has been challenging but with the rapid growth of new treatments for IgA nephropathy it is likely that many of these treatments will, over time, transition to the treatment of recurrent disease. In this narrative review, our aim is to evaluate post-transplant IgA nephropathy in terms of epidemiology, risk factors, underlying pathophysiology, diagnosis and management strategies.
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuN/A
dc.identifier.doi10.1007/s40620-024-02149-6
dc.identifier.eissn1724-6059
dc.identifier.issn1121-8428
dc.identifier.quartileQ2
dc.identifier.scopus2-s2.0-85209687995
dc.identifier.urihttps://doi.org/10.1007/s40620-024-02149-6
dc.identifier.urihttps://hdl.handle.net/20.500.14288/27650
dc.identifier.wos1359525400001
dc.keywordsKidney transplantation
dc.keywordsIgA nephropathy
dc.keywordsRecurrence
dc.keywordsSodium-glucose cotransporter-2 inhibitors
dc.keywordsAngiotensin converting enzyme inhibitors
dc.keywordsAngiotensin receptor blockers
dc.language.isoeng
dc.publisherSpringer Heidelberg
dc.relation.ispartofJournal of Nephrology
dc.subjectUrology and nephrology
dc.titlePost-transplant IgA nephropathy: a rapidly evolving field of kidney transplant medicine
dc.typeReview
dspace.entity.typePublication
local.contributor.kuauthorKanbay, Mehmet
local.contributor.kuauthorÇöpür, Sidar
local.contributor.kuauthorÖzbek, Laşin
local.contributor.kuauthorGüldan, Mustafa
local.publication.orgunit1SCHOOL OF MEDICINE
local.publication.orgunit2School of Medicine
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relation.isParentOrgUnitOfPublication17f2dc8e-6e54-4fa8-b5e0-d6415123a93e
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