Publication:
Engineering molecular machines

dc.contributor.departmentDepartment of Chemical and Biological Engineering
dc.contributor.kuauthorErman, Burak
dc.contributor.schoolcollegeinstituteCollege of Engineering
dc.date.accessioned2024-11-09T12:13:06Z
dc.date.issued2016
dc.description.abstractBiological molecular motors use chemical energy, mostly in the form of ATP hydrolysis, and convert it to mechanical energy. Correlated thermal fluctuations are essential for the function of a molecular machine and it is the hydrolysis of ATP that modifies the correlated fluctuations of the system. Correlations are consequences of the molecular architecture of the protein. The idea that synthetic molecular machines may be constructed by designing the proper molecular architecture is challenging. In their paper, Sarkar et al (2016 New J. Phys. 18 043006) propose a synthetic molecular motor based on the coarse grained elastic network model of proteins and show by numerical simulations that motor function is realized, ranging from deterministic to thermal, depending on temperature. This work opens up a new range of possibilities of molecular architecture based engine design.
dc.description.fulltextYES
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.openaccessYES
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuN/A
dc.description.sponsorshipN/A
dc.description.versionPublisher version
dc.description.volume18
dc.identifier.doi10.1088/1367-2630/18/4/041002
dc.identifier.embargoNO
dc.identifier.filenameinventorynoIR00537
dc.identifier.issn1367-2630
dc.identifier.quartileQ2
dc.identifier.scopus2-s2.0-85013786844
dc.identifier.urihttps://hdl.handle.net/20.500.14288/1213
dc.identifier.wos375464000001
dc.keywordsMolecular machines
dc.keywordsThermal fluctuations
dc.keywordsAllostery
dc.keywordsStiffness
dc.keywordsGaussian network model
dc.keywordsElastic net
dc.language.isoeng
dc.publisherInstitute of Physics (IOP) Publishing
dc.relation.ispartofNew Journal of Physics
dc.relation.urihttp://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/600
dc.subjectMultidisciplinary physics
dc.titleEngineering molecular machines
dc.typeJournal Article
dspace.entity.typePublication
local.contributor.kuauthorErman, Burak
local.publication.orgunit1College of Engineering
local.publication.orgunit2Department of Chemical and Biological Engineering
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