Publication:
A retina-ınspired optoelectronic synapse using quantum dots for neuromorphic photostimulation of neurons

dc.contributor.departmentKUTTAM (Koç University Research Center for Translational Medicine)
dc.contributor.departmentDepartment of Electrical and Electronics Engineering
dc.contributor.departmentGraduate School of Sciences and Engineering
dc.contributor.departmentSchool of Medicine
dc.contributor.kuauthorKaleli, Humeyra Nur
dc.contributor.kuauthorNizamoğlu, Sedat
dc.contributor.kuauthorBalamur, Rıdvan
dc.contributor.kuauthorKaya, Lokman
dc.contributor.kuauthorEren, Güncem Özgün
dc.contributor.kuauthorHasanreisoğlu, Murat
dc.contributor.schoolcollegeinstituteCollege of Engineering
dc.contributor.schoolcollegeinstituteGRADUATE SCHOOL OF SCIENCES AND ENGINEERING
dc.contributor.schoolcollegeinstituteResearch Center
dc.contributor.schoolcollegeinstituteSCHOOL OF MEDICINE
dc.date.accessioned2025-01-19T10:28:55Z
dc.date.issued2024
dc.description.abstractNeuromorphic electronics, inspired by the functions of neurons, have the potential to enable biomimetic communication with cells. Such systems require operation in aqueous environments, generation of sufficient levels of ionic currents for neurostimulation, and plasticity. However, their implementation requires a combination of separate devices, such as sensors, organic synaptic transistors, and stimulation electrodes. Here, a compact neuromorphic synapse that combines photodetection, memory, and neurostimulation functionalities all-in-one is presented. The artificial photoreception is facilitated by a photovoltaic device based on cell-interfacing InP/ZnS quantum dots, which induces photo-faradaic charge-transfer mediated plasticity. The device sends excitatory post-synaptic currents exhibiting paired-pulse facilitation and post-tetanic potentiation to the hippocampal neurons via the biohybrid synapse. The electrophysiological recordings indicate modulation of the probability of action potential firing due to biomimetic temporal summation of excitatory post-synaptic currents. These results pave the way for the development of novel bioinspired neuroprosthetics and soft robotics, and highlight the potential of quantum dots for achieving versatile neuromorphic functionality in aqueous environments. In this work, a compact neuromorphic synapse that combines photodetection, memory, and neurostimulation functionalities all-in-one is presented. The photovoltaic device based on cell-interfacing InP/ZnS quantum dots induces photo-faradaic charge-transfer mediated plasticity. The electrophysiological recordings indicate modulation of the probability of action potential firing due to biomimetic temporal summation of excitatory post-synaptic currents.
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.issue20
dc.description.openaccessgold, Green Submitted
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuN/A
dc.description.sponsorshipThe authors thank Dr. Baris Yagci from the Koc University Surface Science and Technology Center (KUYTAM) for the SEM images. The authors thank Dr. Amir Motallebzadeh from KUYTAM for helping with oxygen plasma sterilization. The authors thank Dr. Gulcan Corapcioglu for HR-TEM images. The authors gratefully acknowledge use of the services and facilities of the Koc University Research Center for Translational Medicine (KUTTAM), funded by The Scientific and Technological Research Council of Turkiye (TUBITAK) (Grant No. 120E329). The content is solely the responsibility of the authors and does not necessarily represent the official views of the Ministry of Development.
dc.description.volume11
dc.identifier.doi10.1002/advs.202306097
dc.identifier.eissn2198-3844
dc.identifier.quartileQ1
dc.identifier.scopus2-s2.0-85194591968
dc.identifier.urihttps://doi.org/10.1002/advs.202306097
dc.identifier.urihttps://hdl.handle.net/20.500.14288/25785
dc.identifier.wos1188588000001
dc.keywordsNeuromorphic synapse
dc.keywordsPhotovoltaic devices
dc.keywordsQuantum dots
dc.language.isoeng
dc.publisherWiley
dc.relation.grantnoThe Scientific and Technological Research Council of Turkiye (TUBITAK) [120E329]
dc.relation.ispartofAdvanced Science
dc.subjectChemistry, multidisciplinary
dc.subjectNanoscience and nanotechnology
dc.subjectMaterials science, multidisciplinary
dc.titleA retina-ınspired optoelectronic synapse using quantum dots for neuromorphic photostimulation of neurons
dc.typeJournal Article
dspace.entity.typePublication
local.contributor.kuauthorBalamur, Rıdvan
local.contributor.kuauthorEren, Güncem Özgün
local.contributor.kuauthorKaleli, Humeyra Nur
local.contributor.kuauthorKaratum, Onuralp
local.contributor.kuauthorKaya, Lokman
local.contributor.kuauthorHasanreisoğlu, Murat
local.contributor.kuauthorNizamoğlu, Sedat
local.publication.orgunit1GRADUATE SCHOOL OF SCIENCES AND ENGINEERING
local.publication.orgunit1SCHOOL OF MEDICINE
local.publication.orgunit1College of Engineering
local.publication.orgunit1Research Center
local.publication.orgunit2Department of Electrical and Electronics Engineering
local.publication.orgunit2KUTTAM (Koç University Research Center for Translational Medicine)
local.publication.orgunit2School of Medicine
local.publication.orgunit2Graduate School of Sciences and Engineering
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