Publication: Association of myeloid derived suppressor cells and immunosuppressive elements with disease and prognosis in pancreatic adenocarcinoma.
Program
KU-Authors
KU Authors
Co-Authors
Erdal, G. S.
Isiksacan, N.
Gumusoglu, A. Y.
Kabuli, H. A.
Yildiz, T.
Tasci, T. S.
Tas, S. K.
Atar, P.
Editor & Affiliation
Compiler & Affiliation
Translator
Other Contributor
Date
Language
eng
Type
Embargo Status
N/A
Journal Title
Journal ISSN
Volume Title
Alternative Title
Abstract
The aim of this study was to evaluate the roles of myeloid-derived suppressor cells (MDSCs) and immunosuppressive cytokines in different patient groups with pancreatic adenocarcinoma (PAC).Inoperable advanced-stage patients, operable patients (evaluated as preoperative and postoperative), and healthy controls were included.Peripheral blood MDSC subtypes were analyzed by flow cytometry, and cytokines associated with immunosuppression were measured by ELISA.Statistical comparisons were performed to determine variations across clinical groups.Among MDSC subsets, G-MDSCs were markedly elevated in inoperable patients compared with controls (p
Source
Publisher
Tohoku University Medical Press
Subject
LHealth sciences, Medicine
Citation
Has Part
Source
The Tohoku Journal of Experimental Medicine
Book Series Title
Edition
DOI
10.1620/tjem.2026.j017