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Association of myeloid derived suppressor cells and immunosuppressive elements with disease and prognosis in pancreatic adenocarcinoma.

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dc.contributor.coauthorErdal, G. S.
dc.contributor.coauthorIsiksacan, N.
dc.contributor.coauthorGumusoglu, A. Y.
dc.contributor.coauthorKabuli, H. A.
dc.contributor.coauthorYildiz, T.
dc.contributor.coauthorTasci, T. S.
dc.contributor.coauthorTas, S. K.
dc.contributor.coauthorAtar, P.
dc.contributor.departmentKUH (Koç University Hospital)
dc.contributor.kuauthorTural, Deniz
dc.contributor.schoolcollegeinstituteKUH (KOÇ UNIVERSITY HOSPITAL)
dc.date.accessioned2026-07-22T13:08:04Z
dc.date.issued2026
dc.description.abstractThe aim of this study was to evaluate the roles of myeloid-derived suppressor cells (MDSCs) and immunosuppressive cytokines in different patient groups with pancreatic adenocarcinoma (PAC).Inoperable advanced-stage patients, operable patients (evaluated as preoperative and postoperative), and healthy controls were included.Peripheral blood MDSC subtypes were analyzed by flow cytometry, and cytokines associated with immunosuppression were measured by ELISA.Statistical comparisons were performed to determine variations across clinical groups.Among MDSC subsets, G-MDSCs were markedly elevated in inoperable patients compared with controls (p
dc.description.harvestedfromManual
dc.description.indexedbyPubMed
dc.description.publisherscopeInternational
dc.description.readpublishN/A
dc.description.sponsoredbyTubitakEuN/A
dc.description.versionPublished Version
dc.identifier.doi10.1620/tjem.2026.j017
dc.identifier.eissn1349-3329
dc.identifier.embargoN/A
dc.identifier.issn0040-8727
dc.identifier.pubmed42386547
dc.identifier.urihttp://doi.org/10.1620/tjem.2026.j017
dc.identifier.urihttps://hdl.handle.net/20.500.14288/33734
dc.keywordsDisease
dc.keywordsMyeloid-derived suppressor cell
dc.keywordsSuppressor
dc.keywordsAdenocarcinoma
dc.keywordsMyeloid
dc.keywordsImmune system
dc.languageeng
dc.publisherTohoku University Medical Press
dc.relation.affiliationKoç University
dc.relation.collectionKoç University Institutional Repository
dc.relation.ispartofThe Tohoku Journal of Experimental Medicine
dc.subjectLHealth sciences
dc.subjectMedicine
dc.titleAssociation of myeloid derived suppressor cells and immunosuppressive elements with disease and prognosis in pancreatic adenocarcinoma.
dc.typeJournal Article
dspace.entity.typePublication
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relation.isParentOrgUnitOfPublication.latestForDiscovery055775c9-9efe-43ec-814f-f6d771fa6dee

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