Publication:
Choroidal vascularity index in pseudoexfoliative glaucoma

dc.contributor.coauthorOzum, Yucel
dc.contributor.coauthorAltan, Çigdem
dc.contributor.departmentKUH (Koç University Hospital)
dc.contributor.departmentSchool of Medicine
dc.contributor.kuauthorKarslıoğlu, Melisa Zişan
dc.contributor.kuauthorKesim, Cem
dc.contributor.kuauthorTaş, Ayşe Yıldız
dc.contributor.kuauthorŞahin, Afsun
dc.contributor.kuauthorTorun, Şafak
dc.contributor.kuprofileDoctor
dc.contributor.kuprofileDoctor
dc.contributor.kuprofileFaculty Member
dc.contributor.kuprofileFaculty Member
dc.contributor.kuprofileUndergraduate Student
dc.contributor.schoolcollegeinstituteSCHOOL OF MEDICINE
dc.contributor.schoolcollegeinstituteKUH (KOÇ UNIVERSITY HOSPITAL)
dc.contributor.yokidN/A
dc.contributor.yokid387367
dc.contributor.yokid200905
dc.contributor.yokid171267
dc.contributor.yokidN/A
dc.date.accessioned2024-11-09T23:23:14Z
dc.date.issued2021
dc.description.abstractPurpose To evaluate choroidal vascular involvement in pseudoexfoliative glaucoma (PEXG) by applying the choroidal vascularity index (CVI) to optic coherence tomography (OCT) images. Methods Seventy-eight eyes from 40 subjects were included the study. Group 1 included healthy eyes (n = 20), group 2 eyes with PEX (n = 16), and group 3 eyes with PEXG (n = 42). OCT imaging of macular and peripapillary regions and retinal nerve fiber layer (RNFL) analyses were performed. CVI was calculated using ImageJ software. Results The mean age was 64.89 +/- 5.8, 71.2 +/- 7.8, and 68.24 +/- 7.4 years in groups 1, 2, and 3, respectively (p = 0.046). There were no significant differences between the groups in terms of sex (p = 0.777). In macula, mean CVI rates were 66.97 +/- 1.9%, 64.23 +/- 1.2%, and 64.63 +/- 1.6%, and in the peripapillary areas, mean CVI rates were 67.04 +/- 1.5%, 65.20 +/- 1.5%, and 64.14 +/- 2.1% in groups 1, 2, and 3, respectively (group 1 vs. group 2 and 3, p = 0.000; group 2 vs. group 3, p > 0.05). The decrease in average RNFL thickness was statistically significant in group 3 compared to groups 1 and 2. Conclusion CVI could be used to assess choroidal vascular changes in ocular diseases. CVI was found to be reduced in PEX and PEXG, indicating an ocular vascular involvement in pseudoexfoliative process.
dc.description.indexedbyWoS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.issue12
dc.description.openaccessNO
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuN/A
dc.description.volume41
dc.identifier.doi10.1007/s10792-021-01990-z
dc.identifier.eissn1573-2630
dc.identifier.issn0165-5701
dc.identifier.quartileQ3
dc.identifier.scopus2-s2.0-85111814737
dc.identifier.urihttp://dx.doi.org/10.1007/s10792-021-01990-z
dc.identifier.urihttps://hdl.handle.net/20.500.14288/11204
dc.identifier.wos681582100001
dc.keywordsChoroidal vascularity index
dc.keywordsPseudoexfoliation syndrome
dc.keywordsPseudoexfoliative glaucoma
dc.keywordsNerve-fiber layer
dc.keywordsMicrovasculature dropout
dc.keywordsExfoliation syndrome
dc.keywordsStructural-changes
dc.keywordsParameters
dc.keywordsThickness
dc.keywordsEyes
dc.keywordsAge
dc.languageEnglish
dc.publisherSpringer
dc.sourceInternational Ophthalmology
dc.subjectOphthalmology
dc.titleChoroidal vascularity index in pseudoexfoliative glaucoma
dc.typeJournal Article
dspace.entity.typePublication
local.contributor.authorid0000-0002-7665-4508
local.contributor.authorid0000-0001-6747-1534
local.contributor.authorid0000-0003-1716-5488
local.contributor.authorid0000-0002-5083-5618
local.contributor.authoridN/A
local.contributor.kuauthorKarslıoğlu, Melisa Zişan
local.contributor.kuauthorKesim, Cem
local.contributor.kuauthorTaş, Ayşe Yıldız
local.contributor.kuauthorŞahin, Afsun
local.contributor.kuauthorTorun, Şafak
local.publication.orgunit1SCHOOL OF MEDICINE
local.publication.orgunit1KUH (KOÇ UNIVERSITY HOSPITAL)
local.publication.orgunit2KUH (Koç University Hospital)
local.publication.orgunit2School of Medicine
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