Publication:
Predictive value of nutrition and inflammation-related indices on prognosis in type 2 diabetes mellitus patients with Coronavirus Disease-2019

dc.contributor.coauthorEkici, Mustafa
dc.contributor.coauthorMenekse, Tugba Sanalp
dc.contributor.coauthorCiftciler, Rafiye
dc.contributor.departmentKUH (Koç University Hospital)
dc.contributor.departmentSchool of Medicine
dc.contributor.kuauthorBatman, Adnan
dc.contributor.kuauthorDereli, Dilek Yazıcı
dc.contributor.schoolcollegeinstituteKUH (KOÇ UNIVERSITY HOSPITAL)
dc.contributor.schoolcollegeinstituteSCHOOL OF MEDICINE
dc.date.accessioned2024-12-29T09:38:52Z
dc.date.issued2023
dc.description.abstractObjectives: This study aimed to demonstrate how the prognostic nutritional index (PNI) and systemic immune -inflammatory index (SII) help predict the severity and prognosis of patients with type 2 diabetes (T2DM) and coronavirus disease (Covid-19). Methods: This retrospective cohort study included 501 T2DM patients (male, 42.1%; female, 57.9%) who were hospitalized due to Covid-19 between April 2020 and December 2020. The patients were divided into survivors and non -survivors. After comparing demographic and laboratory data between the groups, the correlation of PNI and SII with clinical and laboratory data was evaluated. Results: The median (interquartile) ages of the non -survivor and survivor groups were 74 (15) and 69 (14) years, respectively, and the difference was significant (p<0.001). The PNI was significantly lower in the non -survivor group than in the survivor group (p<0.001). The SII was significantly higher in the non-survivor group than in the survivor group (p<0.001). PNI was negatively correlated with glucose levels (r=-0.115, p=0.011). If the cut-off PNI value of 29.1 was used, it had a sensitivity and specificity of 76.2% and 76.3%, respectively, in predicting the severity of the illness and the risk of death in T2DM patients. Conclusion: Consequently, the PNI and SII levels are effective in predicting survival and disease severity in patients with Covid-19 and T2DM.
dc.description.indexedbyWOS
dc.description.indexedbyPubMed
dc.description.issue1
dc.description.openaccessBronze, Green Accepted
dc.description.publisherscopeNational
dc.description.sponsoredbyTubitakEuN/A
dc.description.volume58
dc.identifier.doi10.14744/SEMB.2023.36699
dc.identifier.eissn1308-5123
dc.identifier.issn1302-7123
dc.identifier.quartileQ3
dc.identifier.urihttps://doi.org/10.14744/SEMB.2023.36699
dc.identifier.urihttps://hdl.handle.net/20.500.14288/22830
dc.identifier.wos1201788800008
dc.keywordsCoronavirus disease-2019
dc.keywordsPrognostic nutritional index
dc.keywordsSystemic immune-inflammatory index
dc.keywordsType 2 diabetes mellitus
dc.language.isoeng
dc.publisherKARE PUBL
dc.relation.ispartofMEDICAL BULLETIN OF SISLI ETFAL HOSPITAL
dc.subjectMedicine
dc.subjectGeneral
dc.subjectInternal
dc.titlePredictive value of nutrition and inflammation-related indices on prognosis in type 2 diabetes mellitus patients with Coronavirus Disease-2019
dc.typeJournal Article
dspace.entity.typePublication
local.contributor.kuauthorBatman, Adnan
local.contributor.kuauthorDereli, Dilek Yazıcı
local.publication.orgunit1SCHOOL OF MEDICINE
local.publication.orgunit1KUH (KOÇ UNIVERSITY HOSPITAL)
local.publication.orgunit2KUH (Koç University Hospital)
local.publication.orgunit2School of Medicine
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