Publication:
A new scoring system to predict survival in elderly advanced stage Hodgkin lymphoma patients

dc.contributor.coauthorMehtap,Ozgur
dc.contributor.coauthorToptas,Tayfur
dc.contributor.coauthorDal,Mehmet S.
dc.contributor.coauthorKaradag,Fatma Keklik
dc.contributor.coauthorAtas,Unal
dc.contributor.coauthorOzsan,Guner H.
dc.contributor.coauthorSayinalp,Nilguen
dc.contributor.coauthorSaydam,Guray
dc.contributor.coauthorUcar,Mehmet Ali
dc.contributor.coauthorKirkizlar,Hakki Onur
dc.contributor.coauthorSalim,Ozan
dc.contributor.coauthorTekinalp,Atakan
dc.contributor.coauthorOzkalemkas,Fahir
dc.contributor.coauthorPepedi,Funda
dc.contributor.coauthorKilicaslan,Emrah
dc.contributor.coauthorPaydas,Semra
dc.contributor.coauthorBozdag,Sinem Civriz
dc.contributor.coauthorYilmaz,Mehmet
dc.contributor.coauthorKarakus,Volkan
dc.contributor.coauthorArikan,Fatma Gecgel
dc.contributor.coauthorDarcin,Tahir
dc.contributor.coauthorErdogan,Elcin
dc.contributor.coauthorCinar,Erkin
dc.contributor.coauthorGursoy,Vildan
dc.contributor.coauthorDurusoy,Salih S.
dc.contributor.coauthorAtesoglu,Elif Birtas
dc.contributor.coauthorTombak,Anil
dc.contributor.coauthorBuyukkurt,Nurhilal
dc.contributor.coauthorOzcan,Muhit
dc.contributor.coauthorAltuntas,Fevzi
dc.contributor.coauthorAtagunduz,Isik Kaygusuz
dc.contributor.departmentSchool of Medicine
dc.contributor.kuauthorAkay, Olga Meltem
dc.contributor.kuauthorFerhanoğlu, Ahmet Burhan
dc.contributor.schoolcollegeinstituteSCHOOL OF MEDICINE
dc.date.accessioned2025-03-06T20:59:26Z
dc.date.issued2024
dc.description.abstractPredictive prognostic scoring (PS) systems are not primarily applicable to elderly patients with classical Hodgkin lymphoma (cHL). The objective of this study was to develop a PS system for these patients. The derivation cohort (DC) was utilized for model development, consisting of 97 variables. The resulting algorithm was named as Hodgkin's Lymphoma Early Death in the Elderly within 12 months (HEDEL12). Internal and external validation cohorts (IVC and EVC) were employed for validation. A total of 286 patients were evaluated retrospectively. In DC 38 of 178 patients died within the first 12 months and overall survival (OS) at 12-month was 78.6%. Independent predictors of HEDEL12 were female sex, low albumin levels (<3.5 g/dL), and ECOG scores 2-4. According to HEDEL12 scores 0-1, OS at 12- months were 89.8% and 91.0% for IVC and EVC, respectively. The HEDEL12 scoring is useful in predicting the survival of advanced-stage cHL patients.
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.publisherscopeInternational
dc.description.sponsoredbyTubitakEuN/A
dc.identifier.doi10.1080/10428194.2024.2395458
dc.identifier.eissn1029-2403
dc.identifier.issn1042-8194
dc.identifier.issue14
dc.identifier.quartileQ3
dc.identifier.scopus2-s2.0-85204028151
dc.identifier.urihttps://doi.org/10.1080/10428194.2024.2395458
dc.identifier.urihttps://hdl.handle.net/20.500.14288/27703
dc.identifier.volume65
dc.identifier.wos1313272800001
dc.keywordsElderly hodgkin lymphoma
dc.keywordsPrognostic scoring
dc.keywordsAdvanced stage
dc.language.isoeng
dc.publisherTaylor and Francis
dc.relation.ispartofLeukemia and Lymphoma
dc.subjectOncology
dc.subjectHematology
dc.titleA new scoring system to predict survival in elderly advanced stage Hodgkin lymphoma patients
dc.typeJournal Article
dc.type.otherEarly access
dspace.entity.typePublication
local.contributor.kuauthorAkay, Olga Meltem
local.contributor.kuauthorFerhanoğlu, Ahmet Burhan
local.publication.orgunit1SCHOOL OF MEDICINE
local.publication.orgunit2School of Medicine
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