Publication:
A review of bioresorbable implantable medical devices: materials, fabrication, and implementation

dc.contributor.departmentDepartment of Mechanical Engineering
dc.contributor.departmentGraduate School of Sciences and Engineering
dc.contributor.kuauthorBathaei, Mohammad Javad
dc.contributor.kuauthorBeker, Levent
dc.contributor.kuauthorİstif, Emin
dc.contributor.kuauthorSingh, Rahul
dc.contributor.schoolcollegeinstituteCollege of Engineering
dc.contributor.schoolcollegeinstituteGRADUATE SCHOOL OF SCIENCES AND ENGINEERING
dc.date.accessioned2024-11-09T23:10:00Z
dc.date.issued2020
dc.description.abstractImplantable medical devices (IMDs) are designed to sense specific parameters or stimulate organs and have been actively used for treatment and diagnosis of various diseases. IMDs are used for long-term disease screening or treatments and cannot be considered for short-term applications since patients need to go through a surgery for retrieval of the IMD. Advances in bioresorbable materials has led to the development of transient IMDs that can be resorbed by bodily fluids and disappear after a certain period. These devices are designed to be implanted in the adjacent of the targeted tissue for predetermined times with the aim of measurement of pressure, strain, or temperature, while the bioelectronic devices stimulate certain tissues. They enable opportunities for monitoring and treatment of acute diseases. To realize such transient and miniaturized devices, researchers utilize a variety of materials, novel fabrication methods, and device design strategies. This review discusses potential bioresorbable materials for each component in an IMD followed by programmable degradation and safety standards. Then, common fabrication methods for bioresorbable materials are introduced, along with challenges. The final section provides representative examples of bioresorbable IMDs for various applications with an emphasis on materials, device functionality, and fabrication methods.
dc.description.indexedbyWOS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.issue18
dc.description.openaccessNO
dc.description.sponsoredbyTubitakEuTÜBİTAK
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK) 2232 [118C295]
dc.description.sponsorshipMarie Sklodowska-Curie Individual Fellowship [H2020-MSCA-IF-2018-840786] M.J.B. and L.B. are supported by The Scientific and Technological Research Council of Turkey (TUBITAK) 2232 (funding #118C295). L.B. acknowledges the support through a Marie Sklodowska-Curie Individual Fellowship (H2020-MSCA-IF-2018-840786).
dc.description.volume9
dc.identifier.doi10.1002/adhm.202000790
dc.identifier.eissn2192-2659
dc.identifier.issn2192-2640
dc.identifier.scopus2-s2.0-85089368478
dc.identifier.urihttps://doi.org/10.1002/adhm.202000790
dc.identifier.urihttps://hdl.handle.net/20.500.14288/9384
dc.identifier.wos559389100001
dc.keywordsBioresorbable sensors
dc.keywordsFabrication techniques
dc.keywordsImplantable medical devices
dc.keywordsTransient medical devices
dc.keywordsTriggering mechanisms
dc.keywordsEnzymatic degradation
dc.keywordsMechanical-properties
dc.keywordsTransient electronics
dc.keywordsPorous silicon
dc.keywordsSilk fibroin
dc.keywordsIn-vivo
dc.keywordsBiodegradable elastomers
dc.keywordsPoly(butylene succinate)
dc.keywordsCrystalline regions
dc.keywordsTemperature sensor
dc.language.isoeng
dc.publisherWiley
dc.relation.ispartofAdvanced Healthcare Materials
dc.subjectEngineering
dc.subjectBiomedical engineering
dc.subjectNanoscience
dc.subjectNanotechnology
dc.subjectMaterials sciences
dc.subjectBiomedical materials
dc.titleA review of bioresorbable implantable medical devices: materials, fabrication, and implementation
dc.typeReview
dspace.entity.typePublication
local.contributor.kuauthorSingh, Rahul
local.contributor.kuauthorBathaei, Mohammad Javad
local.contributor.kuauthorİstif, Emin
local.contributor.kuauthorBeker, Levent
local.publication.orgunit1GRADUATE SCHOOL OF SCIENCES AND ENGINEERING
local.publication.orgunit1College of Engineering
local.publication.orgunit2Department of Mechanical Engineering
local.publication.orgunit2Graduate School of Sciences and Engineering
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