Publication:
Multiparametric mri guidance in first-time prostate biopsies: what is the real benefit?

dc.contributor.coauthorColakoglu, Bulent
dc.contributor.coauthorVural, Metin
dc.contributor.coauthorSaglican, Yesim
dc.contributor.coauthorTuerkbey, Baris
dc.contributor.departmentN/A
dc.contributor.kuauthorAcar, Ömer
dc.contributor.kuauthorEsen, Tarık
dc.contributor.kuauthorOnay, Aslıhan
dc.contributor.kuauthorRozanes, İzzet
dc.contributor.kuprofileFaculty Member
dc.contributor.kuprofileFaculty Member
dc.contributor.kuprofileDoctor
dc.contributor.kuprofileFaculty Member
dc.contributor.schoolcollegeinstituteSchool of Medicine
dc.contributor.schoolcollegeinstituteSchool of Medicine
dc.contributor.schoolcollegeinstituteN/A
dc.contributor.schoolcollegeinstituteSchool of Medicine
dc.contributor.unitN/A
dc.contributor.unitN/A
dc.contributor.unitKoç Universitiy Hospital
dc.contributor.unitN/A
dc.contributor.yokid237530
dc.contributor.yokid50536
dc.contributor.yokidN/A
dc.contributor.yokid125890
dc.date.accessioned2024-11-09T23:35:27Z
dc.date.issued2015
dc.description.abstractPURPOSE With the increased recognition of the capabilities of prostate multiparametric (mp) magnetic resonance imaging (MRI), attempts are being made to incorporate MRI into routine prostate biopsies. In this study, we aimed to analyze the diagnostic yield via cognitive fusion, transrectal ultrasound (TRUS)-guided, and in-bore MRI-guided biopsies in biopsy-naive patients with positive findings for prostate cancer screening. METHODS Charts of 140 patients, who underwent transrectal prostate biopsy after the adaptation of mp-MRI into our routine clinical practice, were reviewed retrospectively. Patients with previous negative biopsies (n=24) and digital rectal examination findings suspicious for >= cT3 prostate cancer (n=16) were excluded. T2-weighted imaging, diffusion-weighted imaging, and dynamic contrast-enhanced imaging were included in mp-MRI. Cognitive fusion biopsies were performed after a review of mp-MRI data, whereas TRUS-guided biopsies were performed blinded to MRI information. In-bore biopsies were conducted by means of real-time targeting under MRI guidance. RESULTS Between January 2012 and February 2014, a total of 100 patients fulfilling the inclusion criteria underwent TRUS-guided (n=37), cognitive fusion (n=49), and in-bore (n=14) biopsies. Mean age, serum prostate specific antigen level, and prostate size did not differ significantly among the study groups. In TRUS-guided biopsy group, 51.3% were diagnosed with prostate cancer, while the same ratio was 55.1% and 71.4% in cognitive fusion and in-bore biopsy groups, respectively (P = 0.429). Clinically significant prostate cancer detection rate was 69.1%, 70.3%, and 90% in TRUS-guided, cognitive fusion, and in-bore biopsy groups, respectively (P = 0.31). According to histopathologic variables in the prostatectomy specimen, significant prostate cancer was detected in 85.7%, 93.3%, and 100% of patients in TRUS-guided, cognitive fusion, and in-bore biopsy groups, respectively. CONCLUSION In the first set of transrectal prostate biopsies, mp-MRI guidance did not increase the diagnostic yield significantly.
dc.description.indexedbyWoS
dc.description.indexedbyScopus
dc.description.indexedbyPubMed
dc.description.indexedbyTR Dizin
dc.description.issue4
dc.description.openaccessYES
dc.description.publisherscopeNational
dc.description.sponsoredbyTubitakEuN/A
dc.description.volume21
dc.identifier.doi10.5152/dir.2015.46014
dc.identifier.eissn1305-3612
dc.identifier.issn1305-3825
dc.identifier.scopus2-s2.0-84936095481
dc.identifier.urihttp://dx.doi.org/10.5152/dir.2015.46014
dc.identifier.urihttps://hdl.handle.net/20.500.14288/12505
dc.identifier.wos357332300002
dc.keywordsUltrasound fusion
dc.keywordsCancer detection
dc.keywordsResonance
dc.keywordsAntigen
dc.keywordsMen
dc.keywordsEra
dc.languageEnglish
dc.publisherTurkish Soc Radiology
dc.sourceDiagnostic and Interventional Radiology
dc.subjectRadiology, nuclear medicine
dc.subjectMedical imaging
dc.titleMultiparametric mri guidance in first-time prostate biopsies: what is the real benefit?
dc.typeJournal Article
dspace.entity.typePublication
local.contributor.authorid0000-0002-6094-9264
local.contributor.authorid0000-0002-0961-9374
local.contributor.authorid0000-0003-4213-9126
local.contributor.authorid0000-0002-1178-7449
local.contributor.kuauthorAcar, Ömer
local.contributor.kuauthorEsen, Tarık
local.contributor.kuauthorOnay, Aslıhan
local.contributor.kuauthorRozanes, İzzet

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